Tag: drug shelf-life

Managing API Degradation in Sugar-Coated Tablets During Stability Studies

June 4, 2025 Admin

Managing API Degradation in Sugar-Coated Tablets During Stability Studies Managing API Degradation in Sugar-Coated Tablets During Stability Studies Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of a drug product throughout its shelf life is of paramount importance. Sugar-coated tablets, a popular dosage form due to their aesthetic appeal and ease of ingestion,…

Solid Dosage form, Tablets

Evaluating Effect of Packaging Interactions on Stability of Sustained Release Tablets

May 30, 2025 Admin

Evaluating Effect of Packaging Interactions on Stability of Sustained Release Tablets Evaluating Effect of Packaging Interactions on Stability of Sustained Release Tablets Introduction: In the pharmaceutical industry, ensuring the stability of sustained release tablets is paramount to maintaining efficacy and safety. These tablets are designed to release active ingredients over an extended period, offering advantages…

Solid Dosage form, Tablets

Resolving Brittleness in Immediate Release Tablets During Long-Term Storage

May 26, 2025 Admin

Resolving Brittleness in Immediate Release Tablets During Long-Term Storage Resolving Brittleness in Immediate Release Tablets During Long-Term Storage Introduction: Immediate release tablets are a cornerstone of pharmaceutical dosage forms, designed to disintegrate promptly after administration to ensure rapid drug release. However, maintaining their integrity during long-term storage poses significant challenges. One of the most critical…

Solid Dosage form, Tablets

Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets

May 8, 2025 Admin

Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of enteric-coated tablets is critical. These tablets are specifically designed to pass through the stomach intact and dissolve in the intestine. Moisture exposure can compromise the integrity…

Solid Dosage form, Tablets

Ensuring Packaging Compatibility for Tablets with Extended Stability Requirements

May 4, 2025 Admin

Ensuring Packaging Compatibility for Tablets with Extended Stability Requirements Ensuring Packaging Compatibility for Tablets with Extended Stability Requirements Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of tablets throughout their shelf life is paramount. This is particularly critical for tablets with extended stability requirements. The compatibility between the packaging and the tablet formulation…

Solid Dosage form, Tablets

Troubleshooting Surface Roughness in Sugar-Coated Tablets During Storage

April 30, 2025 Admin

Troubleshooting Surface Roughness in Sugar-Coated Tablets During Storage Troubleshooting Surface Roughness in Sugar-Coated Tablets During Storage Introduction: Sugar-coated tablets are a prevalent form of oral pharmaceutical dosage due to their aesthetic appeal, taste masking abilities, and protective properties. However, during storage, these tablets can sometimes develop surface roughness, which can compromise their appearance, consumer acceptance,…

Solid Dosage form, Tablets

Investigating Impact of Oxidative Stress on Coated Tablet Stability

April 25, 2025 Admin

Investigating Impact of Oxidative Stress on Coated Tablet Stability Investigating Impact of Oxidative Stress on Coated Tablet Stability Introduction: In the pharmaceutical industry, the stability of coated tablets is a critical factor in ensuring drug efficacy and safety over their shelf life. Coated tablets are designed to protect the active pharmaceutical ingredients (APIs) from environmental…

Solid Dosage form, Tablets

Addressing Impact of Oxidative Stress on Sugar-Coated Tablets

April 11, 2025 Admin

Addressing Impact of Oxidative Stress on Sugar-Coated Tablets Addressing Impact of Oxidative Stress on Sugar-Coated Tablets Introduction: In the pharmaceutical industry, the stability of drug formulations is paramount to ensuring efficacy and safety. Among the various solid dosage forms, sugar-coated tablets offer unique benefits such as taste masking and protection of active ingredients. However, these…

Solid Dosage form, Tablets

Poor correlation between accelerated and real-time stability results.

March 12, 2025 Admin

Poor correlation between accelerated and real-time stability results. Poor correlation between accelerated and real-time stability results. Introduction: Stability testing is an essential component of the pharmaceutical development process. It ensures that a drug product maintains its intended physical, chemical, microbiological, and therapeutic properties throughout its shelf life. Accelerated stability testing and real-time stability testing are…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Optimizing Stability Testing Conditions for Hygroscopic Tablets

March 4, 2025 Admin

Optimizing Stability Testing Conditions for Hygroscopic Tablets Optimizing Stability Testing Conditions for Hygroscopic Tablets Introduction: Hygroscopic tablets, known for their moisture-absorbing properties, pose unique challenges in the realm of pharmaceutical product stability. Stability testing is a crucial component in the lifecycle of drug development, ensuring that a product maintains its integrity, efficacy, and safety throughout…

Solid Dosage form, Tablets

Addressing Non-Compliance in Stability Testing for Coated Tablets

March 1, 2025 Admin

Addressing Non-Compliance in Stability Testing for Coated Tablets Addressing Non-Compliance in Stability Testing for Coated Tablets Introduction: Stability testing is a critical component in the pharmaceutical industry, ensuring that drugs maintain their efficacy, safety, and quality over time. For coated tablets, this becomes even more crucial due to the additional complexity introduced by the coating…

Solid Dosage form, Tablets