Tag: Drug Safety

Managing API Degradation in Sugar-Coated Tablets During Stability Studies

June 4, 2025 Admin

Managing API Degradation in Sugar-Coated Tablets During Stability Studies Managing API Degradation in Sugar-Coated Tablets During Stability Studies Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of a drug product throughout its shelf life is of paramount importance. Sugar-coated tablets, a popular dosage form due to their aesthetic appeal and ease of ingestion,…

Solid Dosage form, Tablets

Addressing Residual Solvent Build-Up in Sugar-Coating Pans During Validation

May 25, 2025 Admin

Addressing Residual Solvent Build-Up in Sugar-Coating Pans During Validation Addressing Residual Solvent Build-Up in Sugar-Coating Pans During Validation Introduction: The sugar-coating process in pharmaceutical manufacturing plays a crucial role in enhancing the aesthetic appeal, taste masking, and stability of tablets. However, managing residual solvent build-up during this process, particularly in the coating pans, is a…

Solid Dosage form, Tablets

Managing Cross-Contamination Risks in Coating Machines Used for Extended Release Tablets

May 23, 2025 Admin

Managing Cross-Contamination Risks in Coating Machines Used for Extended Release Tablets Managing Cross-Contamination Risks in Coating Machines Used for Extended Release Tablets Introduction: In the pharmaceutical industry, ensuring product safety and efficacy is paramount, and one critical aspect of this is managing cross-contamination risks. This is especially crucial in the production of extended-release tablets, where…

Solid Dosage form, Tablets

Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging

May 18, 2025 Admin

Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging Ensuring Adequate Moisture Barrier in Sugar-Coated Tablet Packaging Introduction: Sugar-coated tablets have been a mainstay in pharmaceutical formulations for decades. Their aesthetic appeal, taste masking, and ability to protect the active pharmaceutical ingredient (API) are among their numerous advantages. However, the hygroscopic nature of sugar poses a…

Solid Dosage form, Tablets

Managing Material Compatibility Issues in Packaging for Coated Tablets

May 17, 2025 Admin

Managing Material Compatibility Issues in Packaging for Coated Tablets Managing Material Compatibility Issues in Packaging for Coated Tablets Introduction: In the pharmaceutical industry, the packaging of coated tablets is a critical process that ensures the safety, efficacy, and longevity of the product. Coated tablets, designed to enhance stability, control release, and improve patient compliance, require…

Solid Dosage form, Tablets

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets

May 17, 2025 Admin

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the safety and integrity of drug products is paramount. Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestine, providing targeted…

Solid Dosage form, Tablets

Addressing Cross-Contamination Risks in Shared Tablet Manufacturing Equipment

May 5, 2025 Admin

Addressing Cross-Contamination Risks in Shared Tablet Manufacturing Equipment Addressing Cross-Contamination Risks in Shared Tablet Manufacturing Equipment Introduction: In the pharmaceutical industry, ensuring the safety and efficacy of drug products is paramount. With the increasing demand for diverse medications, many manufacturers utilize shared equipment for tablet production to optimize resources. However, shared equipment can pose significant…

Solid Dosage form, Tablets

Ensuring Robustness in QA Monitoring for Immediate Release Tablets

May 5, 2025 Admin

Ensuring Robustness in QA Monitoring for Immediate Release Tablets Ensuring Robustness in QA Monitoring for Immediate Release Tablets Introduction: Quality Assurance (QA) in the pharmaceutical industry is a critical component that ensures the safety, efficacy, and quality of medicinal products. For immediate release tablets, which are designed to disintegrate and release their active pharmaceutical ingredients…

Solid Dosage form, Tablets

Preventing Incorrect Barcode Printing on Tablet Packaging Materials

May 2, 2025 Admin

Preventing Incorrect Barcode Printing on Tablet Packaging Materials Preventing Incorrect Barcode Printing on Tablet Packaging Materials Introduction: In the pharmaceutical industry, accurate barcode printing on packaging is crucial for ensuring patient safety, regulatory compliance, and efficient supply chain management. Barcodes facilitate the tracking and tracing of pharmaceutical products, aiding in the prevention of counterfeit drugs…

Solid Dosage form, Tablets

Inadequate systems for verifying capsule tamper-resistance features.

April 27, 2025 Admin

Inadequate systems for verifying capsule tamper-resistance features. Inadequate Systems for Verifying Capsule Tamper-Resistance Features Introduction: Ensuring the integrity and safety of pharmaceuticals is paramount in the healthcare industry. Capsules, as one of the most prevalent solid oral dosage forms, require robust tamper-resistance features to protect against contamination, counterfeiting, and unauthorized access. However, inadequate systems for…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Investigating Impact of Oxidative Stress on Coated Tablet Stability

April 25, 2025 Admin

Investigating Impact of Oxidative Stress on Coated Tablet Stability Investigating Impact of Oxidative Stress on Coated Tablet Stability Introduction: In the pharmaceutical industry, the stability of coated tablets is a critical factor in ensuring drug efficacy and safety over their shelf life. Coated tablets are designed to protect the active pharmaceutical ingredients (APIs) from environmental…

Solid Dosage form, Tablets

Preventing Seal Integrity Failures in Multi-Layer Blister Packs

April 23, 2025 Admin

Preventing Seal Integrity Failures in Multi-Layer Blister Packs Preventing Seal Integrity Failures in Multi-Layer Blister Packs Introduction: In the pharmaceutical industry, ensuring the integrity of packaging is paramount to safeguarding the efficacy and safety of medicinal products. Multi-layer blister packs are a popular choice due to their ability to protect sensitive pharmaceuticals from environmental factors…

Solid Dosage form, Tablets