Tag: Drug formulation

Troubleshooting Non-Conformance in Dissolution Testing Protocols

May 26, 2025 Admin

Troubleshooting Non-Conformance in Dissolution Testing Protocols Troubleshooting Non-Conformance in Dissolution Testing Protocols Introduction: Dissolution testing plays a crucial role in the pharmaceutical industry, ensuring that solid dosage forms like tablets release their active ingredients at the desired rate. When these protocols encounter non-conformance, it can lead to significant setbacks in drug development and manufacturing. Understanding…

Solid Dosage form, Tablets

Managing Material Compatibility Issues in Packaging for Coated Tablets

May 17, 2025 Admin

Managing Material Compatibility Issues in Packaging for Coated Tablets Managing Material Compatibility Issues in Packaging for Coated Tablets Introduction: In the pharmaceutical industry, the packaging of coated tablets is a critical process that ensures the safety, efficacy, and longevity of the product. Coated tablets, designed to enhance stability, control release, and improve patient compliance, require…

Solid Dosage form, Tablets

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets

May 17, 2025 Admin

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the safety and integrity of drug products is paramount. Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestine, providing targeted…

Solid Dosage form, Tablets

Investigating API Potency Retention in Immediate Release Tablets Over Time

May 11, 2025 Admin

Investigating API Potency Retention in Immediate Release Tablets Over Time Investigating API Potency Retention in Immediate Release Tablets Over Time Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of medicinal products is paramount. One critical aspect of this is the potency retention of the Active Pharmaceutical Ingredient (API) in immediate release tablets over…

Solid Dosage form, Tablets

Managing API Migration in Multi-API Tablets During Stability Testing

May 11, 2025 Admin

Managing API Migration in Multi-API Tablets During Stability Testing Managing API Migration in Multi-API Tablets During Stability Testing Introduction: In the ever-evolving world of pharmaceuticals, the development of multi-active pharmaceutical ingredient (API) tablets has gained significant momentum. These formulations offer the advantage of delivering multiple therapeutic effects in a single dose, enhancing patient compliance and…

Solid Dosage form, Tablets

Optimizing Desiccant Placement for Sustained Release Tablet Packaging

May 9, 2025 Admin

Optimizing Desiccant Placement for Sustained Release Tablet Packaging Optimizing Desiccant Placement for Sustained Release Tablet Packaging Introduction: In the pharmaceutical industry, the integrity of drug products is paramount, particularly for sustained release tablets that require precise control over their release mechanisms. A crucial aspect of ensuring the efficacy and safety of these medications is effective…

Solid Dosage form, Tablets

Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets

May 8, 2025 Admin

Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of enteric-coated tablets is critical. These tablets are specifically designed to pass through the stomach intact and dissolve in the intestine. Moisture exposure can compromise the integrity…

Solid Dosage form, Tablets

Troubleshooting Failures in Layer Adhesion During Bilayer Tablet Equipment Validation

May 6, 2025 Admin

Troubleshooting Failures in Layer Adhesion During Bilayer Tablet Equipment Validation Troubleshooting Failures in Layer Adhesion During Bilayer Tablet Equipment Validation Introduction: Bilayer tablets have emerged as a significant advancement in pharmaceutical dosage forms, offering the potential for controlled release, improved patient compliance, and enhanced therapeutic efficacy. However, their manufacturing presents unique challenges, particularly concerning layer…

Solid Dosage form, Tablets

Ensuring Robustness in QA Monitoring for Immediate Release Tablets

May 5, 2025 Admin

Ensuring Robustness in QA Monitoring for Immediate Release Tablets Ensuring Robustness in QA Monitoring for Immediate Release Tablets Introduction: Quality Assurance (QA) in the pharmaceutical industry is a critical component that ensures the safety, efficacy, and quality of medicinal products. For immediate release tablets, which are designed to disintegrate and release their active pharmaceutical ingredients…

Solid Dosage form, Tablets

Ensuring Robustness of Coating Adhesion in Multi-API Tablets Over Time

May 4, 2025 Admin

Ensuring Robustness of Coating Adhesion in Multi-API Tablets Over Time Ensuring Robustness of Coating Adhesion in Multi-API Tablets Over Time Introduction: In the dynamic landscape of pharmaceutical manufacturing, ensuring the robustness of coating adhesion in multi-API (Active Pharmaceutical Ingredient) tablets is crucial. The coating plays a pivotal role in protecting the drug, controlling its release,…

Solid Dosage form, Tablets

Managing Surface Erosion in Sugar-Coated Tablets During Stability Studies

May 3, 2025 Admin

Managing Surface Erosion in Sugar-Coated Tablets During Stability Studies Managing Surface Erosion in Sugar-Coated Tablets During Stability Studies Introduction: In the pharmaceutical industry, sugar-coated tablets have been a popular choice for delivering active pharmaceutical ingredients (APIs) due to their aesthetic appeal, ease of swallowing, and ability to mask the taste of certain drugs. However, during…

Solid Dosage form, Tablets

Ensuring Consistency in Disintegration Time During Long-Term Stability Studies

May 3, 2025 Admin

Ensuring Consistency in Disintegration Time During Long-Term Stability Studies Ensuring Consistency in Disintegration Time During Long-Term Stability Studies Introduction: In the realm of pharmaceuticals, ensuring consistency in the disintegration time of tablets during long-term stability studies is pivotal for guaranteeing a drug’s efficacy, safety, and patient compliance. Disintegration time is a critical quality attribute that…

Solid Dosage form, Tablets