Tag: Drug delivery systems

Preventing Non-Uniform Thickness in Enteric-Coated Tablet Layers

March 24, 2025 Admin

Preventing Non-Uniform Thickness in Enteric-Coated Tablet Layers Preventing Non-Uniform Thickness in Enteric-Coated Tablet Layers Introduction: In the pharmaceutical industry, enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral or alkaline environment of the intestine. This functionality is crucial for protecting active pharmaceutical ingredients (APIs) that are…

Solid Dosage form, Tablets

Resolving Issues in Acid Resistance Tests for Enteric-Coated Tablets

March 24, 2025 Admin

Resolving Issues in Acid Resistance Tests for Enteric-Coated Tablets Resolving Issues in Acid Resistance Tests for Enteric-Coated Tablets Introduction: Enteric-coated tablets are a sophisticated pharmaceutical dosage form designed to resist the acidic environment of the stomach and release active pharmaceutical ingredients (APIs) in the more neutral pH of the intestines. This controlled release profile is…

Solid Dosage form, Tablets

Ensuring Tearability of Strip Packaging for Pediatric Use Tablets

March 22, 2025 Admin

Ensuring Tearability of Strip Packaging for Pediatric Use Tablets Ensuring Tearability of Strip Packaging for Pediatric Use Tablets Introduction: The pharmaceutical industry constantly strives to make medications more accessible and safer, particularly for vulnerable populations like children. Strip packaging, a widely used method for solid dosage forms like tablets, offers several benefits, including protection from…

Solid Dosage form, Tablets

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing

March 22, 2025 Admin

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Introduction: In the pharmaceutical industry, enteric-coated tablets play a crucial role in ensuring that active pharmaceutical ingredients (APIs) are delivered to the intestine, bypassing the acidic environment of the stomach. This not only protects the drug from…

Solid Dosage form, Tablets

Ensuring Robustness in Acidic Media Resistance for Enteric-Coated Tablets

March 21, 2025 Admin

Ensuring Robustness in Acidic Media Resistance for Enteric-Coated Tablets Ensuring Robustness in Acidic Media Resistance for Enteric-Coated Tablets Introduction: Enteric-coated tablets are a pivotal component of modern pharmaceutical formulations, designed to withstand the acidic conditions of the stomach and release the active ingredient in the more neutral pH environment of the intestines. This targeted delivery…

Solid Dosage form, Tablets

Managing Tablet Core Erosion in Enteric-Coated Tablets

March 21, 2025 Admin

Managing Tablet Core Erosion in Enteric-Coated Tablets Managing Tablet Core Erosion in Enteric-Coated Tablets Introduction: Enteric-coated tablets represent a sophisticated drug delivery system designed to bypass the acidic environment of the stomach and to release their active ingredients in the more neutral pH of the intestines. This method of delivery is essential for drugs that…

Solid Dosage form, Tablets

Difficulty in validating capsule filling equipment for lipid-based suspensions.

March 20, 2025 Admin

Difficulty in validating capsule filling equipment for lipid-based suspensions. Difficulty in validating capsule filling equipment for lipid-based suspensions. Introduction: In the pharmaceutical industry, the encapsulation of lipid-based suspensions presents unique challenges that require meticulous validation of capsule filling equipment. Lipid-based formulations are gaining popularity due to their ability to enhance the bioavailability of poorly water-soluble…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Failures in Coating Integrity Testing for Enteric Tablets

March 19, 2025 Admin

Troubleshooting Failures in Coating Integrity Testing for Enteric Tablets Troubleshooting Failures in Coating Integrity Testing for Enteric Tablets Introduction: Enteric tablets are designed to withstand the acidic environment of the stomach, dissolving only in the more neutral pH of the intestine. This protective mechanism is achieved through a specialized coating that ensures the active ingredients…

Solid Dosage form, Tablets

High variability in content uniformity testing for multi-drug capsules.

March 18, 2025 Admin

High variability in content uniformity testing for multi-drug capsules. High Variability in Content Uniformity Testing for Multi-Drug Capsules Introduction: Content uniformity is a critical quality attribute in the manufacturing of pharmaceuticals, ensuring that each dose in a batch contains the intended amount of active pharmaceutical ingredients (APIs). In the context of multi-drug capsules, achieving content…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule disintegration testing for gelatin-free capsules.

March 17, 2025 Admin

Poor validation of capsule disintegration testing for gelatin-free capsules. Poor validation of capsule disintegration testing for gelatin-free capsules. Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of oral dosage forms is paramount. Capsules, both hard and soft gelatin, have been widely used due to their ability to encapsulate a variety of formulations. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule filling processes for multi-layer capsules.

March 16, 2025 Admin

Difficulty in validating capsule filling processes for multi-layer capsules. Difficulty in Validating Capsule Filling Processes for Multi-layer Capsules Introduction: In the ever-evolving pharmaceutical industry, capsule formulations have become a pivotal aspect of oral dosage forms. Multi-layer capsules, offering innovative solutions for drug release, combination therapies, and patient compliance, are gaining popularity. However, the complexity of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating capsule coating processes.

March 14, 2025 Admin

Challenges in validating capsule coating processes. Challenges in Validating Capsule Coating Processes Introduction: In the pharmaceutical industry, the coating of capsules—both hard and soft gelatin—is a critical step in ensuring product stability, controlled release, and patient compliance. Validating these coating processes is essential for maintaining product efficacy and safety. This article explores the challenges of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms