Tag: Drug delivery systems

Addressing Challenges in Handling Enteric-Coated Tablets During Blister Packing

June 2, 2025 Admin

Addressing Challenges in Handling Enteric-Coated Tablets During Blister Packing Addressing Challenges in Handling Enteric-Coated Tablets During Blister Packing Introduction: Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the alkaline environment of the intestine. This specialized coating is crucial for the targeted delivery of certain medications, ensuring their efficacy…

Solid Dosage form, Tablets

Evaluating Long-Term Stability of Coating Polymers in Enteric Tablets

May 22, 2025 Admin

Evaluating Long-Term Stability of Coating Polymers in Enteric Tablets Evaluating Long-Term Stability of Coating Polymers in Enteric Tablets Introduction: In the ever-evolving pharmaceutical landscape, ensuring the efficacy and safety of drug delivery systems is paramount. Enteric tablets, designed to withstand the acidic environment of the stomach and release active ingredients in the intestine, rely heavily…

Solid Dosage form, Tablets

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets

May 17, 2025 Admin

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the safety and integrity of drug products is paramount. Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestine, providing targeted…

Solid Dosage form, Tablets

Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets

May 12, 2025 Admin

Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets Introduction: Enteric-coated tablets are a critical part of modern pharmacology, designed to protect active ingredients from the acidic environment of the stomach and ensure release in the more neutral pH of the intestine. This targeted delivery system…

Solid Dosage form, Tablets

Investigating Coating Adhesion Failures in Enteric-Coated Tablets During Testing

May 10, 2025 Admin

Investigating Coating Adhesion Failures in Enteric-Coated Tablets During Testing Investigating Coating Adhesion Failures in Enteric-Coated Tablets During Testing Introduction: Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral environment of the intestines. This targeted drug delivery system is crucial for drugs that are sensitive to stomach…

Solid Dosage form, Tablets

Challenges in achieving uniform capsule transparency during validation.

May 3, 2025 Admin

Challenges in achieving uniform capsule transparency during validation. Challenges in achieving uniform capsule transparency during validation. Introduction: In the pharmaceutical industry, the demand for consistent and high-quality solid oral dosage forms has never been greater. Among these, capsules, particularly hard and soft gelatin capsules, stand out due to their versatility and consumer preference for ease…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Poor Coating Adhesion in Extended Release Tablets Over Time

May 3, 2025 Admin

Troubleshooting Poor Coating Adhesion in Extended Release Tablets Over Time Troubleshooting Poor Coating Adhesion in Extended Release Tablets Over Time Introduction: Extended release tablets are a crucial aspect of modern pharmaceutical delivery systems, offering consistent therapeutic effects over extended periods. However, the integrity of their coating is paramount to ensure proper drug release and efficacy….

Solid Dosage form, Tablets

Problems with maintaining consistent capsule transparency over time.

May 1, 2025 Admin

Problems with maintaining consistent capsule transparency over time. Problems with maintaining consistent capsule transparency over time. Introduction: In the pharmaceutical industry, the appearance of a capsule is not merely an aesthetic concern but a critical quality attribute. Transparency in capsules, especially those made from gelatin, is vital for consumer trust and product acceptance. Over time,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Investigating Non-Uniform Dissolution in Enteric-Coated Tablets During Testing

April 30, 2025 Admin

Investigating Non-Uniform Dissolution in Enteric-Coated Tablets During Testing Investigating Non-Uniform Dissolution in Enteric-Coated Tablets During Testing Introduction: The pharmaceutical industry constantly strives to develop effective drug delivery mechanisms, with enteric-coated tablets serving as a crucial form of solid dosage. These tablets are designed to resist the acidic environment of the stomach, releasing their active ingredients…

Solid Dosage form, Tablets

Poor correlation between in vitro dissolution and stability data.

April 24, 2025 Admin

Poor correlation between in vitro dissolution and stability data. Poor correlation between in vitro dissolution and stability data. Introduction: In the pharmaceutical industry, the correlation between in vitro dissolution and stability data is pivotal for ensuring the efficacy and safety of solid oral dosage forms, particularly capsules. Dissolution testing is a key quality control measure…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring cross-linking in gelatin shells.

April 23, 2025 Admin

Inadequate systems for monitoring cross-linking in gelatin shells. Inadequate Systems for Monitoring Cross-Linking in Gelatin Shells Introduction: In the pharmaceutical industry, gelatin capsules are a popular choice for encapsulating a wide range of medications due to their ease of use, consumer preference, and bioavailability. However, one of the critical quality concerns associated with gelatin capsules,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in evaluating the stability of multi-particulate capsules.

April 23, 2025 Admin

Difficulty in evaluating the stability of multi-particulate capsules. Difficulty in evaluating the stability of multi-particulate capsules Introduction: In the pharmaceutical industry, ensuring the stability of drug products is crucial for maintaining their efficacy, safety, and quality over their shelf life. Multi-particulate capsules, which contain numerous small, discrete particles within a single dosage form, offer several…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms