Tag: Drug delivery

Challenges in predicting the impact of high humidity on capsule disintegration times.

April 30, 2025 Admin

Challenges in predicting the impact of high humidity on capsule disintegration times. Challenges in predicting the impact of high humidity on capsule disintegration times. Introduction: In the realm of pharmaceutical manufacturing, ensuring the efficacy and stability of solid oral dosage forms such as capsules is paramount. Capsules, both hard and soft gelatin, are a prevalent…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in determining the impact of low-temperature storage on capsule shells.

April 7, 2025 Admin

Challenges in determining the impact of low-temperature storage on capsule shells. Challenges in determining the impact of low-temperature storage on capsule shells. Introduction: The pharmaceutical industry significantly relies on capsules as a solid oral dosage form due to their versatility and effectiveness in delivering active pharmaceutical ingredients (APIs). Capsules, whether hard or soft gelatin, provide…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Validating Equipment for High-Speed Compression of Multi-Layer Tablets

April 6, 2025 Admin

Validating Equipment for High-Speed Compression of Multi-Layer Tablets Validating Equipment for High-Speed Compression of Multi-Layer Tablets Introduction: In the pharmaceutical industry, the demand for multi-layer tablets has been increasing due to their ability to deliver multiple drugs with different release profiles in a single dosage form. This has led to the need for high-speed compression…

Solid Dosage form, Tablets

Addressing Coating Layer Delamination in Sustained Release Tablets

March 29, 2025 Admin

Addressing Coating Layer Delamination in Sustained Release Tablets Addressing Coating Layer Delamination in Sustained Release Tablets Introduction: The pharmaceutical industry continually seeks to enhance drug delivery systems, with sustained release tablets being a significant innovation. These tablets are designed to release their active ingredients over an extended period, ensuring a consistent therapeutic effect and improved…

Solid Dosage form, Tablets

Ensuring Uniform Coating Thickness in Irregularly Shaped Tablets

March 18, 2025 Admin

Ensuring Uniform Coating Thickness in Irregularly Shaped Tablets Ensuring Uniform Coating Thickness in Irregularly Shaped Tablets Introduction: In the pharmaceutical industry, tablet coatings serve multiple purposes, including protection from environmental conditions, masking taste, and controlling drug release. Achieving a uniform coating thickness is crucial, especially for irregularly shaped tablets, which present unique challenges. Uniform coatings…

Solid Dosage form, Tablets

Addressing Non-Adherence of Coating Layers in Film-Coated Tablets

March 9, 2025 Admin

Addressing Non-Adherence of Coating Layers in Film-Coated Tablets Addressing Non-Adherence of Coating Layers in Film-Coated Tablets Introduction: Film-coated tablets are a cornerstone of modern pharmaceutical delivery systems, providing benefits such as improved stability, controlled drug release, and enhanced patient compliance. However, challenges such as the non-adherence of coating layers can compromise the efficacy and quality…

Solid Dosage form, Tablets

Optimizing Layer Adhesion in Bilayer Tablet Compression

March 7, 2025 Admin

Optimizing Layer Adhesion in Bilayer Tablet Compression Optimizing Layer Adhesion in Bilayer Tablet Compression Introduction: Bilayer tablets are an innovative solution in the pharmaceutical industry, allowing for the combination of two active ingredients with distinct release profiles or chemical characteristics. This format is crucial in cases where combination therapy is necessary, providing patient convenience and…

Solid Dosage form, Tablets

Managing Challenges in Validating Spray Guns for Enteric-Coating Applications

March 6, 2025 Admin

Managing Challenges in Validating Spray Guns for Enteric-Coating Applications Managing Challenges in Validating Spray Guns for Enteric-Coating Applications Introduction: In the pharmaceutical industry, enteric coating is a critical process used to ensure that the active pharmaceutical ingredient (API) of a tablet survives the acidic environment of the stomach and is released in the intestine, where…

Solid Dosage form, Tablets

Troubleshooting Adhesion Problems in Enteric-Coating Materials

March 4, 2025 Admin

Troubleshooting Adhesion Problems in Enteric-Coating Materials Troubleshooting Adhesion Problems in Enteric-Coating Materials Introduction: In the pharmaceutical industry, the development of solid dosage forms such as tablets is a critical process, where enteric coating plays a vital role. Enteric coatings are designed to withstand the acidic environment of the stomach while dissolving in the more neutral…

Solid Dosage form, Tablets

What are the primary sources of drug candidates in the drug discovery process?

September 16, 2023September 9, 2023 Admin

Sources of Drug Candidates in the Drug Discovery Process Drug candidates are compounds that show potential therapeutic activity and are identified through various approaches to address specific diseases. 1. Chemical Libraries Compound Collections: Large libraries of diverse small molecules with potential drug-like properties. High-Throughput Screening (HTS): Automated assays to test thousands of compounds for activity…

Drug Discovery

What is drug discovery, and why is it important in the pharmaceutical industry?

September 15, 2023September 9, 2023 Admin

Importance of Drug Discovery in the Pharmaceutical Industry As a pharmaceutical expert, I can explain the concept of drug discovery and its paramount importance in the pharmaceutical industry. Drug discovery is the foundational process of identifying and developing new therapeutic compounds to treat various diseases and improve patient outcomes. 1. Defining Drug Discovery Drug discovery…

Drug Discovery

How does R&D address the issue of drug resistance and antimicrobial resistance?

September 14, 2023September 9, 2023 Admin

Addressing Drug Resistance and Antimicrobial Resistance in R&D As a pharmaceutical expert, I can elaborate on how Research and Development (R&D) efforts are dedicated to tackling the critical issues of drug resistance and antimicrobial resistance. These challenges have profound implications for public health, and R&D plays a vital role in developing strategies and solutions to…

Pharma Research