Tag: dissolution testing

Investigating Failures in Dissolution Testing for Sustained Release Tablets

March 22, 2025 Admin

Investigating Failures in Dissolution Testing for Sustained Release Tablets Investigating Failures in Dissolution Testing for Sustained Release Tablets Introduction: The pharmaceutical industry is a cornerstone of modern medicine, with sustained release tablets playing a crucial role in controlled drug delivery systems. These formulations are designed to release the active pharmaceutical ingredient (API) at a predetermined…

Solid Dosage form, Tablets

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing

March 22, 2025 Admin

Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Ensuring Adequate pH Stability in Enteric-Coated Tablets During Testing Introduction: In the pharmaceutical industry, enteric-coated tablets play a crucial role in ensuring that active pharmaceutical ingredients (APIs) are delivered to the intestine, bypassing the acidic environment of the stomach. This not only protects the drug from…

Solid Dosage form, Tablets

Ensuring Robustness in Acidic Media Resistance for Enteric-Coated Tablets

March 21, 2025 Admin

Ensuring Robustness in Acidic Media Resistance for Enteric-Coated Tablets Ensuring Robustness in Acidic Media Resistance for Enteric-Coated Tablets Introduction: Enteric-coated tablets are a pivotal component of modern pharmaceutical formulations, designed to withstand the acidic conditions of the stomach and release the active ingredient in the more neutral pH environment of the intestines. This targeted delivery…

Solid Dosage form, Tablets

Investigating Causes of Non-Uniform Dissolution Profiles in Enteric Tablets

March 21, 2025 Admin

Investigating Causes of Non-Uniform Dissolution Profiles in Enteric Tablets Investigating Causes of Non-Uniform Dissolution Profiles in Enteric Tablets Introduction: Enteric tablets are specially designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestines. This targeted dissolution is critical for drugs that are sensitive to stomach acid…

Solid Dosage form, Tablets

Common Issues in Batch Sampling for Quality Testing of Tablets

March 19, 2025 Admin

Common Issues in Batch Sampling for Quality Testing of Tablets Common Issues in Batch Sampling for Quality Testing of Tablets Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of tablet batches is paramount. Batch sampling is a critical process that involves selecting a representative sample from a production batch to assess the quality…

Solid Dosage form, Tablets

Poor reproducibility in monitoring capsule disintegration times.

March 16, 2025 Admin

Poor reproducibility in monitoring capsule disintegration times. Poor reproducibility in monitoring capsule disintegration times. Introduction: In the realm of pharmaceutical research and manufacturing, ensuring the quality and efficacy of solid oral dosage forms is paramount. Among these, capsules, both hard and soft gelatin, are widely used due to their convenience and efficacy in drug delivery….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Ensuring Consistency in Dissolution Testing for Multi-API Tablets

March 16, 2025 Admin

Ensuring Consistency in Dissolution Testing for Multi-API Tablets Ensuring Consistency in Dissolution Testing for Multi-API Tablets Introduction: Dissolution testing is a critical quality control measure in the pharmaceutical industry, particularly for tablets containing multiple active pharmaceutical ingredients (APIs). Ensuring consistency in dissolution testing is vital as it impacts the tablet’s efficacy, safety, and regulatory compliance….

Solid Dosage form, Tablets

Managing Variability in Dissolution Testing for Immediate Release Tablets

March 16, 2025 Admin

Managing Variability in Dissolution Testing for Immediate Release Tablets Managing Variability in Dissolution Testing for Immediate Release Tablets Introduction: Dissolution testing is a critical quality control measure in the pharmaceutical industry, particularly for immediate release tablets. This test ensures that the tablet releases its active ingredients at the desired rate and extent, which is crucial…

Solid Dosage form, Tablets

Managing Hardness Failures in Bilayer Tablets During Testing

March 15, 2025 Admin

Managing Hardness Failures in Bilayer Tablets During Testing Managing Hardness Failures in Bilayer Tablets During Testing Introduction: In the pharmaceutical industry, bilayer tablets have emerged as a sophisticated solution for delivering multiple drugs or varied release profiles within a single dosage form. This innovation not only enhances patient compliance but also optimizes therapeutic efficacy by…

Solid Dosage form, Tablets

Resolving Failures in Moisture Content Tests for Sugar-Coated Tablets

March 14, 2025 Admin

Resolving Failures in Moisture Content Tests for Sugar-Coated Tablets Resolving Failures in Moisture Content Tests for Sugar-Coated Tablets Introduction: In the pharmaceutical industry, sugar-coated tablets are a popular dosage form due to their aesthetic appeal and ability to mask unpleasant tastes. However, maintaining the correct moisture content in these tablets is crucial, as it affects…

Solid Dosage form, Tablets

Troubleshooting Variability in Dissolution Profiles During Stability Studies

March 14, 2025 Admin

Troubleshooting Variability in Dissolution Profiles During Stability Studies Troubleshooting Variability in Dissolution Profiles During Stability Studies Introduction: Dissolution testing is a critical aspect of pharmaceutical development, acting as a quality control measure to ensure that tablets release their active ingredients at the intended rate and extent. During stability studies, the variability in dissolution profiles can…

Solid Dosage form, Tablets

Resolving Failures in Disintegration Testing for Sustained Release Tablets

March 13, 2025 Admin

Resolving Failures in Disintegration Testing for Sustained Release Tablets Resolving Failures in Disintegration Testing for Sustained Release Tablets Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of solid dosage forms such as tablets is paramount. Sustained release tablets, designed to release a drug at a predetermined rate, present unique challenges in quality control,…

Solid Dosage form, Tablets