Tag: coating process optimization

Troubleshooting Poor Adhesion in Sugar-Coated Tablet Layers

March 28, 2025 Admin

Troubleshooting Poor Adhesion in Sugar-Coated Tablet Layers Troubleshooting Poor Adhesion in Sugar-Coated Tablet Layers Introduction: Sugar-coated tablets are an essential solid dosage form in the pharmaceutical industry, known for their aesthetic appeal and ability to mask unpleasant tastes. However, ensuring the integrity of these coatings is crucial, as poor adhesion between layers can compromise product…

Solid Dosage form, Tablets

Addressing Over-Drying in Sugar-Coated Tablets During Curing

March 27, 2025 Admin

Addressing Over-Drying in Sugar-Coated Tablets During Curing Addressing Over-Drying in Sugar-Coated Tablets During Curing Introduction: Sugar-coating is an essential phase in the production of tablets, offering not only aesthetic appeal but also protection from environmental factors. However, one of the prevalent challenges during the sugar-coating process is over-drying, which can compromise the integrity and effectiveness…

Solid Dosage form, Tablets

Troubleshooting Failures in In-Process Monitoring for Film-Coated Tablets

March 22, 2025 Admin

Troubleshooting Failures in In-Process Monitoring for Film-Coated Tablets Troubleshooting Failures in In-Process Monitoring for Film-Coated Tablets Introduction: In the pharmaceutical industry, film-coated tablets represent a significant portion of solid dosage forms due to their enhanced stability, ease of swallowing, and aesthetic attributes. The coating process is critical, as it affects the tablet’s performance and patient…

Solid Dosage form, Tablets

Preventing Coating Layer Delamination in Extended Release Tablets

March 22, 2025 Admin

Preventing Coating Layer Delamination in Extended Release Tablets Preventing Coating Layer Delamination in Extended Release Tablets Introduction: In the pharmaceutical industry, the development of extended release tablets presents a significant advancement in drug delivery systems. These tablets are engineered to release medication at a predetermined rate, thereby maintaining a consistent drug concentration for an extended…

Solid Dosage form, Tablets

Managing Surface Roughness in Sugar-Coated Tablets After Stability Storage

March 20, 2025 Admin

Managing Surface Roughness in Sugar-Coated Tablets After Stability Storage Managing Surface Roughness in Sugar-Coated Tablets After Stability Storage Introduction: Sugar-coated tablets remain a popular choice in the pharmaceutical industry due to their aesthetic appeal and ability to mask unpleasant tastes. However, maintaining their quality over time, especially during stability storage, presents challenges such as surface…

Solid Dosage form, Tablets

Troubleshooting Failures in Coating Integrity Testing for Enteric Tablets

March 19, 2025 Admin

Troubleshooting Failures in Coating Integrity Testing for Enteric Tablets Troubleshooting Failures in Coating Integrity Testing for Enteric Tablets Introduction: Enteric tablets are designed to withstand the acidic environment of the stomach, dissolving only in the more neutral pH of the intestine. This protective mechanism is achieved through a specialized coating that ensures the active ingredients…

Solid Dosage form, Tablets

Troubleshooting Layer Delamination in Sugar-Coated Tablets During Validation

March 18, 2025 Admin

Troubleshooting Layer Delamination in Sugar-Coated Tablets During Validation Troubleshooting Layer Delamination in Sugar-Coated Tablets During Validation Introduction: In the pharmaceutical industry, sugar-coated tablets are a popular dosage form due to their aesthetic appeal and taste-masking properties. However, during the critical phase of validation, one of the most common issues encountered is layer delamination. This problem…

Solid Dosage form, Tablets

Troubleshooting Uneven Color Distribution in Sugar-Coated Tablets

March 17, 2025 Admin

Troubleshooting Uneven Color Distribution in Sugar-Coated Tablets Troubleshooting Uneven Color Distribution in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a popular dosage form in the pharmaceutical industry due to their ability to mask unpleasant tastes and improve patient compliance. However, achieving a uniform color distribution on these tablets can be challenging. Uneven color distribution not only…

Solid Dosage form, Tablets

Ensuring Even Coating Thickness in Irregularly Shaped Tablets

March 16, 2025 Admin

Ensuring Even Coating Thickness in Irregularly Shaped Tablets Ensuring Even Coating Thickness in Irregularly Shaped Tablets Introduction: In the pharmaceutical industry, tablets are a widely used solid dosage form due to their convenience, stability, and ease of mass production. Coating these tablets serves multiple purposes, including masking unpleasant tastes, enhancing swallowability, and protecting the active…

Solid Dosage form, Tablets

Challenges in validating capsule coating processes.

March 14, 2025 Admin

Challenges in validating capsule coating processes. Challenges in Validating Capsule Coating Processes Introduction: In the pharmaceutical industry, the coating of capsules—both hard and soft gelatin—is a critical step in ensuring product stability, controlled release, and patient compliance. Validating these coating processes is essential for maintaining product efficacy and safety. This article explores the challenges of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Troubleshooting Uneven Spray Patterns in Automated Coating Machines

March 14, 2025 Admin

Troubleshooting Uneven Spray Patterns in Automated Coating Machines Troubleshooting Uneven Spray Patterns in Automated Coating Machines Introduction: In pharmaceutical manufacturing, the coating of tablets is a critical process that enhances product stability, controls drug release, and improves patient compliance. Automated coating machines have revolutionized this process, offering precision and efficiency. However, uneven spray patterns in…

Solid Dosage form, Tablets

Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets

March 13, 2025 Admin

Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets Introduction: Enteric tablets are specially designed solid dosage forms that remain intact in the acidic environment of the stomach and dissolve in the more neutral pH of the intestine. This ensures that active pharmaceutical ingredients (APIs) are released at…

Solid Dosage form, Tablets