Tag: coating integrity

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets

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Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the integrity of film-coated tablets is a critical aspect of product quality and efficacy. Film coatings on tablets serve multiple purposes, including protection from environmental factors, masking unpleasant tastes,…

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Solid Dosage form, Tablets

Evaluating Long-Term Stability of Coating Polymers in Enteric Tablets

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Evaluating Long-Term Stability of Coating Polymers in Enteric Tablets Evaluating Long-Term Stability of Coating Polymers in Enteric Tablets Introduction: In the ever-evolving pharmaceutical landscape, ensuring the efficacy and safety of drug delivery systems is paramount. Enteric tablets, designed to withstand the acidic environment of the stomach and release active ingredients in the intestine, rely heavily…

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Solid Dosage form, Tablets

Managing Material Compatibility Issues in Packaging for Coated Tablets

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Managing Material Compatibility Issues in Packaging for Coated Tablets Managing Material Compatibility Issues in Packaging for Coated Tablets Introduction: In the pharmaceutical industry, the packaging of coated tablets is a critical process that ensures the safety, efficacy, and longevity of the product. Coated tablets, designed to enhance stability, control release, and improve patient compliance, require…

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Solid Dosage form, Tablets

Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets

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Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Addressing Problems in Tamper-Evident Sealing for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the safety and integrity of drug products is paramount. Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestine, providing targeted…

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Solid Dosage form, Tablets

Investigating Solvent Evaporation Effects on Coated Tablets During Storage

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Investigating Solvent Evaporation Effects on Coated Tablets During Storage Investigating Solvent Evaporation Effects on Coated Tablets During Storage Introduction: In the pharmaceutical industry, the stability and integrity of coated tablets during storage are paramount to ensuring their efficacy and safety. Solvent evaporation is a critical factor that can affect the coating’s performance, leading to potential…

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Solid Dosage form, Tablets

Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets

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Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets Troubleshooting Failures in Acid Resistance Testing of Enteric-Coated Tablets Introduction: Enteric-coated tablets are a critical part of modern pharmacology, designed to protect active ingredients from the acidic environment of the stomach and ensure release in the more neutral pH of the intestine. This targeted delivery system…

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Solid Dosage form, Tablets

Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets

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Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets Ensuring Moisture Protection in Primary Packaging for Enteric-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the stability and efficacy of enteric-coated tablets is critical. These tablets are specifically designed to pass through the stomach intact and dissolve in the intestine. Moisture exposure can compromise the integrity…

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Solid Dosage form, Tablets

Managing Surface Erosion in Sugar-Coated Tablets During Stability Studies

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Managing Surface Erosion in Sugar-Coated Tablets During Stability Studies Managing Surface Erosion in Sugar-Coated Tablets During Stability Studies Introduction: In the pharmaceutical industry, sugar-coated tablets have been a popular choice for delivering active pharmaceutical ingredients (APIs) due to their aesthetic appeal, ease of swallowing, and ability to mask the taste of certain drugs. However, during…

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Solid Dosage form, Tablets

Troubleshooting Surface Roughness in Sugar-Coated Tablets During Storage

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Troubleshooting Surface Roughness in Sugar-Coated Tablets During Storage Troubleshooting Surface Roughness in Sugar-Coated Tablets During Storage Introduction: Sugar-coated tablets are a prevalent form of oral pharmaceutical dosage due to their aesthetic appeal, taste masking abilities, and protective properties. However, during storage, these tablets can sometimes develop surface roughness, which can compromise their appearance, consumer acceptance,…

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Solid Dosage form, Tablets

Lack of validated methods for testing capsule coatings.

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Lack of validated methods for testing capsule coatings. Lack of validated methods for testing capsule coatings. Introduction: The pharmaceutical industry relies heavily on solid oral dosage forms, particularly capsules, for drug delivery. Capsules, whether hard or soft gelatin, often require coatings to enhance stability, control release, or mask taste. However, a critical gap persists in…

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Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Managing Layer Separation in Sugar-Coated Tablets Under Accelerated Conditions

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Managing Layer Separation in Sugar-Coated Tablets Under Accelerated Conditions Managing Layer Separation in Sugar-Coated Tablets Under Accelerated Conditions Introduction: Sugar-coated tablets have long been a staple in pharmaceutical formulations, offering benefits such as masking unpleasant tastes, improving tablet appearance, and protecting active pharmaceutical ingredients (APIs) from environmental factors. However, they also present unique challenges, particularly…

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Solid Dosage form, Tablets

Troubleshooting Coating Cracks During Stability Testing

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Troubleshooting Coating Cracks During Stability Testing Troubleshooting Coating Cracks During Stability Testing Introduction: In the pharmaceutical industry, the stability of solid dosage forms, particularly tablets, is critical for ensuring the efficacy and safety of medication over its shelf life. Coating cracks are a prevalent issue encountered during stability testing, which can compromise the protective function…

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Solid Dosage form, Tablets