Tag: coating formulation

Addressing Brittleness in Sugar-Coated Tablets During Validation Studies

May 25, 2025 Admin

Addressing Brittleness in Sugar-Coated Tablets During Validation Studies Addressing Brittleness in Sugar-Coated Tablets During Validation Studies Introduction: Sugar-coated tablets have long been a popular choice in pharmaceutical manufacturing due to their aesthetic appeal, ease of swallowing, and ability to mask the taste of active ingredients. However, the process of sugar coating can introduce brittleness, posing…

Solid Dosage form, Tablets

Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing

May 22, 2025 Admin

Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing Investigating Cracking in Enteric-Coated Tablets Under Accelerated Testing Introduction: Enteric-coated tablets are an essential dosage form in the pharmaceutical industry, designed to withstand the acidic environment of the stomach and release active ingredients in the more neutral environment of the intestine. This protective mechanism not only enhances…

Solid Dosage form, Tablets

Troubleshooting Brittleness in Coated Tablets During Validation Testing

May 21, 2025 Admin

Troubleshooting Brittleness in Coated Tablets During Validation Testing Troubleshooting Brittleness in Coated Tablets During Validation Testing Introduction: In the pharmaceutical industry, tablets are a common and vital dosage form. They offer precise dosing, ease of administration, and stability. However, the process of coating tablets, which enhances their appearance, taste, and stability, can introduce challenges. One…

Solid Dosage form, Tablets

Investigating Coating Adhesion Failures in Enteric-Coated Tablets During Testing

May 10, 2025 Admin

Investigating Coating Adhesion Failures in Enteric-Coated Tablets During Testing Investigating Coating Adhesion Failures in Enteric-Coated Tablets During Testing Introduction: Enteric-coated tablets are designed to withstand the acidic environment of the stomach and dissolve in the more neutral environment of the intestines. This targeted drug delivery system is crucial for drugs that are sensitive to stomach…

Solid Dosage form, Tablets

Managing Failures in Adhesion Testing During Film-Coating Validation

April 5, 2025 Admin

Managing Failures in Adhesion Testing During Film-Coating Validation Managing Failures in Adhesion Testing During Film-Coating Validation Introduction: In the pharmaceutical industry, the film-coating process is critical to the production of high-quality tablets. This process not only enhances the appearance of the tablets but also controls the release of the active ingredients, protects the core from…

Solid Dosage form, Tablets

Troubleshooting Adhesion Issues in Enteric-Coated Tablet Layers

March 31, 2025 Admin

Troubleshooting Adhesion Issues in Enteric-Coated Tablet Layers Troubleshooting Adhesion Issues in Enteric-Coated Tablet Layers Introduction: In the highly regulated field of pharmaceutical manufacturing, ensuring the integrity and functionality of enteric-coated tablets is crucial. These specialized coatings play a vital role in protecting active pharmaceutical ingredients (APIs) from the acidic environment of the stomach, ensuring that…

Solid Dosage form, Tablets

Controlling Over-Spray in Sugar-Coated Tablet Processes

March 23, 2025 Admin

Controlling Over-Spray in Sugar-Coated Tablet Processes Controlling Over-Spray in Sugar-Coated Tablet Processes Introduction: Sugar-coating is a traditional method in the pharmaceutical industry, primarily used to enhance the aesthetic appeal and taste of tablets. However, controlling over-spray during the sugar-coating process is critical to ensuring product quality and compliance with regulatory standards. Over-spray can lead to…

Solid Dosage form, Tablets

Identifying Root Causes of Poor Disintegration in Film-Coated Tablets

March 21, 2025 Admin

Identifying Root Causes of Poor Disintegration in Film-Coated Tablets Identifying Root Causes of Poor Disintegration in Film-Coated Tablets Introduction: Film-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their enhanced stability, ease of ingestion, and ability to mask unpleasant tastes. However, one critical quality attribute for these tablets is their…

Solid Dosage form, Tablets

Ensuring Consistency in Coating Thickness During Stress Testing

March 19, 2025 Admin

Ensuring Consistency in Coating Thickness During Stress Testing Ensuring Consistency in Coating Thickness During Stress Testing Introduction: In the pharmaceutical industry, the coating of tablets is a critical process that ensures not only the aesthetic appeal but also the functional performance of the dosage form. A consistent coating thickness is vital for maintaining the integrity…

Solid Dosage form, Tablets

Addressing Brittleness in Sugar-Coated Tablets Under Freeze-Thaw Cycles

March 15, 2025 Admin

Addressing Brittleness in Sugar-Coated Tablets Under Freeze-Thaw Cycles Addressing Brittleness in Sugar-Coated Tablets Under Freeze-Thaw Cycles Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their aesthetic appeal and ability to mask the taste of active pharmaceutical ingredients (APIs). However, the stability of these tablets can be significantly challenged…

Solid Dosage form, Tablets

Troubleshooting Non-Uniform Coating Distribution in Film-Coated Tablets

March 13, 2025 Admin

Troubleshooting Non-Uniform Coating Distribution in Film-Coated Tablets Troubleshooting Non-Uniform Coating Distribution in Film-Coated Tablets Introduction: Film coating of tablets is a critical process in pharmaceutical manufacturing, offering benefits such as enhanced stability, controlled release, and improved patient compliance. However, achieving a uniform film coating is essential for ensuring the tablet’s efficacy, safety, and appearance. Non-uniform…

Solid Dosage form, Tablets

Troubleshooting Residual Solvent Issues in Sugar-Coated Tablets

March 12, 2025 Admin

Troubleshooting Residual Solvent Issues in Sugar-Coated Tablets Troubleshooting Residual Solvent Issues in Sugar-Coated Tablets Introduction: The pharmaceutical industry is continuously advancing, with an emphasis on improving the quality and safety of its products. One of the critical areas of focus is the formulation and manufacturing of solid dosage forms, particularly sugar-coated tablets. These tablets are…

Solid Dosage form, Tablets