Tag: coating defects

Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs

April 8, 2025 Admin

Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs Addressing Core Erosion in Sugar-Coated Tablets During Validation Runs Introduction: Sugar-coated tablets have been a staple in the pharmaceutical industry, offering a palatable and aesthetically pleasing way to deliver medications. However, the process of sugar coating can present unique challenges, particularly during validation runs, a critical…

Solid Dosage form, Tablets

Managing Failures in Adhesion Testing During Film-Coating Validation

April 5, 2025 Admin

Managing Failures in Adhesion Testing During Film-Coating Validation Managing Failures in Adhesion Testing During Film-Coating Validation Introduction: In the pharmaceutical industry, the film-coating process is critical to the production of high-quality tablets. This process not only enhances the appearance of the tablets but also controls the release of the active ingredients, protects the core from…

Solid Dosage form, Tablets

Troubleshooting Poor Adhesion in Enteric-Coated Tablets During Production

April 1, 2025 Admin

Troubleshooting Poor Adhesion in Enteric-Coated Tablets During Production Troubleshooting Poor Adhesion in Enteric-Coated Tablets During Production Introduction: The production of enteric-coated tablets is a critical process in the pharmaceutical industry, ensuring the delivery of medication to the desired part of the gastrointestinal tract without degradation in the stomach. Enteric coatings protect the active pharmaceutical ingredient…

Solid Dosage form, Tablets

Troubleshooting Adhesion Issues in Enteric-Coated Tablet Layers

March 31, 2025 Admin

Troubleshooting Adhesion Issues in Enteric-Coated Tablet Layers Troubleshooting Adhesion Issues in Enteric-Coated Tablet Layers Introduction: In the highly regulated field of pharmaceutical manufacturing, ensuring the integrity and functionality of enteric-coated tablets is crucial. These specialized coatings play a vital role in protecting active pharmaceutical ingredients (APIs) from the acidic environment of the stomach, ensuring that…

Solid Dosage form, Tablets

Troubleshooting Coating Cracks During Stability Testing

March 31, 2025 Admin

Troubleshooting Coating Cracks During Stability Testing Troubleshooting Coating Cracks During Stability Testing Introduction: In the pharmaceutical industry, the stability of solid dosage forms, particularly tablets, is critical for ensuring the efficacy and safety of medication over its shelf life. Coating cracks are a prevalent issue encountered during stability testing, which can compromise the protective function…

Solid Dosage form, Tablets

Addressing Non-Uniform Coating Failures in Quality Control Checks

March 29, 2025 Admin

Addressing Non-Uniform Coating Failures in Quality Control Checks Addressing Non-Uniform Coating Failures in Quality Control Checks Introduction: In the pharmaceutical industry, the coating of tablets is a critical step that not only enhances the aesthetic appeal of the product but also plays a pivotal role in controlling the release profile, protecting the drug from environmental…

Solid Dosage form, Tablets

Addressing Coating Layer Delamination in Sustained Release Tablets

March 29, 2025 Admin

Addressing Coating Layer Delamination in Sustained Release Tablets Addressing Coating Layer Delamination in Sustained Release Tablets Introduction: The pharmaceutical industry continually seeks to enhance drug delivery systems, with sustained release tablets being a significant innovation. These tablets are designed to release their active ingredients over an extended period, ensuring a consistent therapeutic effect and improved…

Solid Dosage form, Tablets

Troubleshooting Uneven Coating Distribution in Film-Coated Tablets

March 28, 2025 Admin

Troubleshooting Uneven Coating Distribution in Film-Coated Tablets Troubleshooting Uneven Coating Distribution in Film-Coated Tablets Introduction: In the pharmaceutical industry, the film coating of tablets is a critical process that enhances the tablet’s aesthetic appeal, provides protection against environmental factors, and can help in controlling the release of the active pharmaceutical ingredient (API). However, achieving a…

Solid Dosage form, Tablets

Managing Solvent Levels in Film-Coating Processes for Consistency

March 26, 2025 Admin

Managing Solvent Levels in Film-Coating Processes for Consistency Managing Solvent Levels in Film-Coating Processes for Consistency Introduction: In the pharmaceutical industry, the film-coating process of tablets is a crucial step that ensures not only the aesthetic appeal but also the stability and controlled release of the active pharmaceutical ingredients (APIs). Managing solvent levels during this…

Solid Dosage form, Tablets

Identifying Root Causes of Non-Uniform Coating Thickness in Tablets

March 25, 2025 Admin

Identifying Root Causes of Non-Uniform Coating Thickness in Tablets Identifying Root Causes of Non-Uniform Coating Thickness in Tablets Introduction: In the pharmaceutical industry, the coating of tablets is a critical process that ensures not only the aesthetic appeal and patient compliance but also the protection of the active pharmaceutical ingredient (API) from environmental factors. Non-uniform…

Solid Dosage form, Tablets

Troubleshooting Non-Adherence of Coating Layers in Extended Release Tablets

March 22, 2025 Admin

Troubleshooting Non-Adherence of Coating Layers in Extended Release Tablets Troubleshooting Non-Adherence of Coating Layers in Extended Release Tablets Introduction: In the pharmaceutical industry, extended release tablets play a crucial role in delivering medication over a prolonged period, enhancing patient compliance and therapeutic efficacy. However, one of the persistent challenges in their production is the non-adherence…

Solid Dosage form, Tablets

Preventing Coating Layer Delamination in Extended Release Tablets

March 22, 2025 Admin

Preventing Coating Layer Delamination in Extended Release Tablets Preventing Coating Layer Delamination in Extended Release Tablets Introduction: In the pharmaceutical industry, the development of extended release tablets presents a significant advancement in drug delivery systems. These tablets are engineered to release medication at a predetermined rate, thereby maintaining a consistent drug concentration for an extended…

Solid Dosage form, Tablets