Tag: coating challenges

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets

May 31, 2025 Admin

Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Investigating Impact of Humidity on Coating Integrity in Film-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the integrity of film-coated tablets is a critical aspect of product quality and efficacy. Film coatings on tablets serve multiple purposes, including protection from environmental factors, masking unpleasant tastes,…

Solid Dosage form, Tablets

Ensuring Uniform Spray Distribution in Coating Machines During Validation

May 8, 2025 Admin

Ensuring Uniform Spray Distribution in Coating Machines During Validation Ensuring Uniform Spray Distribution in Coating Machines During Validation Introduction: In the pharmaceutical industry, the coating of tablets is a critical operation that serves multiple purposes, including masking unpleasant tastes, protecting active pharmaceutical ingredients (APIs) from environmental factors, and controlling the release of the drug. Ensuring…

Solid Dosage form, Tablets

Troubleshooting Non-Uniform Layer Adhesion in Coating Machines During Validation

May 4, 2025 Admin

Troubleshooting Non-Uniform Layer Adhesion in Coating Machines During Validation Troubleshooting Non-Uniform Layer Adhesion in Coating Machines During Validation Introduction: In the world of pharmaceutical manufacturing, the coating of tablets is a critical step that ensures the delivery of active pharmaceutical ingredients (APIs) with precision and efficacy. A uniform coating not only enhances the aesthetic appeal…

Solid Dosage form, Tablets

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time

April 13, 2025 Admin

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their ability to mask unpleasant tastes and improve patient compliance. However, maintaining the potency of the Active Pharmaceutical Ingredient (API)…

Solid Dosage form, Tablets

Managing Residual Solvents in Solvent-Based Coating Applications

March 26, 2025 Admin

Managing Residual Solvents in Solvent-Based Coating Applications Managing Residual Solvents in Solvent-Based Coating Applications Introduction: The use of solvent-based coatings in the pharmaceutical industry plays a crucial role in enhancing the stability, appearance, and functionality of solid dosage forms such as tablets. However, managing residual solvents in these applications is paramount to ensure the safety,…

Solid Dosage form, Tablets

Troubleshooting Cracking in Enteric-Coated Tablets During Drying

March 19, 2025 Admin

Troubleshooting Cracking in Enteric-Coated Tablets During Drying Troubleshooting Cracking in Enteric-Coated Tablets During Drying Introduction: Enteric-coated tablets are a vital component of modern pharmaceuticals, designed to withstand the acidic environment of the stomach and dissolve in the more neutral pH of the intestine. This targeted delivery is crucial for the efficacy and safety of certain…

Solid Dosage form, Tablets

Ensuring Consistency in Coating Thickness During Stress Testing

March 19, 2025 Admin

Ensuring Consistency in Coating Thickness During Stress Testing Ensuring Consistency in Coating Thickness During Stress Testing Introduction: In the pharmaceutical industry, the coating of tablets is a critical process that ensures not only the aesthetic appeal but also the functional performance of the dosage form. A consistent coating thickness is vital for maintaining the integrity…

Solid Dosage form, Tablets

Addressing Poor Adhesion in Enteric Coating Processes

March 18, 2025 Admin

Addressing Poor Adhesion in Enteric Coating Processes Addressing Poor Adhesion in Enteric Coating Processes Introduction: Enteric coating is a crucial process in the pharmaceutical industry, designed to ensure that tablets withstand the acidic environment of the stomach and release their active ingredients in the more neutral pH of the intestine. However, poor adhesion during the…

Solid Dosage form, Tablets

Ensuring Uniform Coating Thickness in Irregularly Shaped Tablets

March 18, 2025 Admin

Ensuring Uniform Coating Thickness in Irregularly Shaped Tablets Ensuring Uniform Coating Thickness in Irregularly Shaped Tablets Introduction: In the pharmaceutical industry, tablet coatings serve multiple purposes, including protection from environmental conditions, masking taste, and controlling drug release. Achieving a uniform coating thickness is crucial, especially for irregularly shaped tablets, which present unique challenges. Uniform coatings…

Solid Dosage form, Tablets

Troubleshooting Non-Homogeneous Color Distribution in Sugar-Coated Tablets

March 17, 2025 Admin

Troubleshooting Non-Homogeneous Color Distribution in Sugar-Coated Tablets Troubleshooting Non-Homogeneous Color Distribution in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry, offering advantages such as ease of swallowing, masking of unpleasant tastes, and aesthetic appeal. However, achieving a consistent and uniform color distribution during the sugar-coating process can be…

Solid Dosage form, Tablets

Ensuring Even Coating Thickness in Irregularly Shaped Tablets

March 16, 2025 Admin

Ensuring Even Coating Thickness in Irregularly Shaped Tablets Ensuring Even Coating Thickness in Irregularly Shaped Tablets Introduction: In the pharmaceutical industry, tablets are a widely used solid dosage form due to their convenience, stability, and ease of mass production. Coating these tablets serves multiple purposes, including masking unpleasant tastes, enhancing swallowability, and protecting the active…

Solid Dosage form, Tablets

Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers

March 15, 2025 Admin

Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers Addressing Non-Uniform Thickness in Enteric-Coated Tablet Layers Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of medicinal products is paramount. Enteric-coated tablets are designed to release their active ingredients in the intestine rather than the stomach, which is crucial for drugs that are sensitive to stomach…

Solid Dosage form, Tablets