Tag: coating adhesion

Troubleshooting Layer Delamination in Sugar-Coated Tablets During Validation

March 18, 2025 Admin

Troubleshooting Layer Delamination in Sugar-Coated Tablets During Validation Troubleshooting Layer Delamination in Sugar-Coated Tablets During Validation Introduction: In the pharmaceutical industry, sugar-coated tablets are a popular dosage form due to their aesthetic appeal and taste-masking properties. However, during the critical phase of validation, one of the most common issues encountered is layer delamination. This problem…

Solid Dosage form, Tablets

Troubleshooting Non-Uniform Coating Distribution in Film-Coated Tablets

March 13, 2025 Admin

Troubleshooting Non-Uniform Coating Distribution in Film-Coated Tablets Troubleshooting Non-Uniform Coating Distribution in Film-Coated Tablets Introduction: Film coating of tablets is a critical process in pharmaceutical manufacturing, offering benefits such as enhanced stability, controlled release, and improved patient compliance. However, achieving a uniform film coating is essential for ensuring the tablet’s efficacy, safety, and appearance. Non-uniform…

Solid Dosage form, Tablets

Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets

March 13, 2025 Admin

Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets Troubleshooting Non-Adherence of Coating Materials in Enteric Tablets Introduction: Enteric tablets are specially designed solid dosage forms that remain intact in the acidic environment of the stomach and dissolve in the more neutral pH of the intestine. This ensures that active pharmaceutical ingredients (APIs) are released at…

Solid Dosage form, Tablets

Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets

March 13, 2025 Admin

Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets Validating Equipment Used for High-Speed Coating of Sugar-Coated Tablets Introduction: In the pharmaceutical industry, the coating of tablets plays a crucial role in the product’s performance and patient acceptability. High-speed coating of sugar-coated tablets is a sophisticated process that necessitates precise equipment validation to ensure consistent…

Solid Dosage form, Tablets

Resolving Sticking Issues in Bottle Filling of Sugar-Coated Tablets

March 11, 2025 Admin

Resolving Sticking Issues in Bottle Filling of Sugar-Coated Tablets Resolving Sticking Issues in Bottle Filling of Sugar-Coated Tablets Introduction: Sugar-coated tablets are a preferred dosage form due to their palatable taste and aesthetic appeal. However, during the bottle filling process, sticking issues can occur, posing significant challenges to pharmaceutical manufacturers. These issues can lead to…

Solid Dosage form, Tablets

Resolving Coating Integrity Issues in Enteric-Coated Tablets

March 9, 2025 Admin

Resolving Coating Integrity Issues in Enteric-Coated Tablets Resolving Coating Integrity Issues in Enteric-Coated Tablets Introduction: Enteric-coated tablets are a critical component of modern pharmaceutical formulations. These specialized coatings are designed to withstand the acidic environment of the stomach, ensuring that the active pharmaceutical ingredient (API) is released in the more neutral pH of the small…

Solid Dosage form, Tablets

Addressing Coating Peel-Off During Stability Studies

March 8, 2025 Admin

Addressing Coating Peel-Off During Stability Studies Addressing Coating Peel-Off During Stability Studies Introduction: In the realm of pharmaceutical manufacturing, ensuring the stability and integrity of tablet coatings is paramount. Coatings play a crucial role in protecting the active pharmaceutical ingredient (API), controlling release profiles, improving patient compliance, and enhancing the aesthetic appeal of the product….

Solid Dosage form, Tablets

Managing Failures in Adhesion Testing During Enteric-Coating Validation

March 6, 2025 Admin

Managing Failures in Adhesion Testing During Enteric-Coating Validation Managing Failures in Adhesion Testing During Enteric-Coating Validation Introduction: Enteric coating is a critical process in the pharmaceutical industry, designed to protect active ingredients from the acidic environment of the stomach and release them in the more neutral pH of the intestine. This process not only ensures…

Solid Dosage form, Tablets

Troubleshooting Spray Coating Defects in Film-Coated Tablets

March 5, 2025 Admin

Troubleshooting Spray Coating Defects in Film-Coated Tablets Troubleshooting Spray Coating Defects in Film-Coated Tablets Introduction: Film coating is a critical process in pharmaceutical tablet manufacturing, providing not only an aesthetic appeal but also functional benefits such as modified release, taste masking, and protection of active pharmaceutical ingredients (APIs) from environmental factors. However, spray coating defects…

Solid Dosage form, Tablets

Addressing High Friability in Sugar-Coated Tablets

March 4, 2025 Admin

Addressing High Friability in Sugar-Coated Tablets Addressing High Friability in Sugar-Coated Tablets Introduction: Sugar-coated tablets are a popular solid dosage form due to their appealing appearance, taste masking capabilities, and ability to protect the drug core from environmental factors. However, achieving the ideal balance between coating thickness and tablet robustness is crucial to maintain product…

Solid Dosage form, Tablets

Troubleshooting Adhesion Problems in Enteric-Coating Materials

March 4, 2025 Admin

Troubleshooting Adhesion Problems in Enteric-Coating Materials Troubleshooting Adhesion Problems in Enteric-Coating Materials Introduction: In the pharmaceutical industry, the development of solid dosage forms such as tablets is a critical process, where enteric coating plays a vital role. Enteric coatings are designed to withstand the acidic environment of the stomach while dissolving in the more neutral…

Solid Dosage form, Tablets

Addressing Failures in Adhesion Tests for Enteric-Coated Tablets

March 3, 2025 Admin

Addressing Failures in Adhesion Tests for Enteric-Coated Tablets Addressing Failures in Adhesion Tests for Enteric-Coated Tablets Introduction: Enteric-coated tablets have revolutionized the pharmaceutical industry by providing a targeted delivery system that ensures the active pharmaceutical ingredient (API) is released in the intestine rather than the stomach. This is crucial for drugs that can be inactivated…

Solid Dosage form, Tablets