Tag: capsule stability

Difficulty in preventing capsule deformation during shrink wrapping.

April 3, 2025 Admin

Difficulty in preventing capsule deformation during shrink wrapping. Difficulty in preventing capsule deformation during shrink wrapping. Introduction: In the pharmaceutical industry, ensuring the integrity of solid oral dosage forms such as capsules is paramount. Capsules, whether hard or soft gelatin, are popular for their ease of administration and precise dosage delivery. However, their delicate structure…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule drying processes for dual-layer capsules.

April 2, 2025 Admin

Difficulty in validating capsule drying processes for dual-layer capsules. Difficulty in validating capsule drying processes for dual-layer capsules Introduction: The pharmaceutical industry is constantly evolving, with innovations aimed at improving drug delivery systems and enhancing patient compliance. One such innovation is the development of dual-layer capsules. These capsules offer the advantage of delivering multiple drugs…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in conducting root cause analysis for capsule quality failures.

April 2, 2025 Admin

Difficulty in conducting root cause analysis for capsule quality failures. Difficulty in conducting root cause analysis for capsule quality failures. Introduction: The pharmaceutical industry is tasked with the critical responsibility of ensuring that all medicinal products are safe, effective, and of the highest quality. Capsules, both hard and soft gelatin, are among the most common…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in vacuum sealing of capsule containers.

April 1, 2025 Admin

Poor reproducibility in vacuum sealing of capsule containers. Poor Reproducibility in Vacuum Sealing of Capsule Containers Introduction: In the pharmaceutical industry, ensuring the integrity and stability of capsule packaging is crucial. Capsules, whether hard or soft gelatin, are sensitive to environmental factors such as moisture and oxygen, which can compromise their efficacy and shelf life….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor control of environmental conditions in packing areas.

March 29, 2025 Admin

Poor control of environmental conditions in packing areas. Poor control of environmental conditions in packing areas. Introduction: The pharmaceutical industry is heavily reliant on maintaining stringent environmental conditions to ensure product quality and safety, especially in the packing areas. Poor control of these conditions can lead to compromised product integrity, impacting patient safety and regulatory…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in assessing stability of capsules containing hygroscopic excipients.

March 28, 2025 Admin

Difficulty in assessing stability of capsules containing hygroscopic excipients. Difficulty in Assessing Stability of Capsules Containing Hygroscopic Excipients Introduction: In the pharmaceutical industry, the stability of drug formulations is paramount to ensuring efficacy and safety. Capsules, both hard and soft gelatin, are popular solid oral dosage forms due to their convenience and patient compliance. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in maintaining consistent capsule integrity during high-speed packing.

March 25, 2025 Admin

Difficulty in maintaining consistent capsule integrity during high-speed packing. Difficulty in maintaining consistent capsule integrity during high-speed packing. Introduction: In the fast-paced world of pharmaceutical manufacturing, maintaining consistent capsule integrity during high-speed packing can pose significant challenges. Capsules, whether hard or soft gelatin, are popular solid oral dosage forms due to their ease of administration…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in evaluating the stability of capsules stored under vacuum-sealed conditions.

March 19, 2025 Admin

Difficulty in evaluating the stability of capsules stored under vacuum-sealed conditions. Difficulty in evaluating the stability of capsules stored under vacuum-sealed conditions. Introduction: The stability of pharmaceutical capsules is a pivotal concern for the industry, ensuring that these dosage forms maintain their efficacy and safety over the intended shelf life. With advancements in packaging technologies,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate sealing of blister packs, leading to moisture ingress.

March 18, 2025 Admin

Inadequate sealing of blister packs, leading to moisture ingress. Inadequate sealing of blister packs, leading to moisture ingress. Introduction: Blister packs are a widely used packaging solution in the pharmaceutical industry, offering protection and extending the shelf life of solid oral dosage forms such as capsules. However, inadequate sealing of blister packs can lead to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule disintegration testing for gelatin-free capsules.

March 17, 2025 Admin

Poor validation of capsule disintegration testing for gelatin-free capsules. Poor validation of capsule disintegration testing for gelatin-free capsules. Introduction: In the pharmaceutical industry, ensuring the efficacy and safety of oral dosage forms is paramount. Capsules, both hard and soft gelatin, have been widely used due to their ability to encapsulate a variety of formulations. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule fill weight variations during long-term storage.

March 16, 2025 Admin

Inadequate systems for monitoring capsule fill weight variations during long-term storage. Inadequate Systems for Monitoring Capsule Fill Weight Variations During Long-Term Storage Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms, particularly capsules, is crucial. Capsules, whether hard or soft gelatin, are popular due to their ease of administration…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor correlation between accelerated and real-time stability results.

March 12, 2025 Admin

Poor correlation between accelerated and real-time stability results. Poor correlation between accelerated and real-time stability results. Introduction: Stability testing is an essential component of the pharmaceutical development process. It ensures that a drug product maintains its intended physical, chemical, microbiological, and therapeutic properties throughout its shelf life. Accelerated stability testing and real-time stability testing are…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms