Tag: capsule shell integrity]

Problems with detecting minor defects in capsule shells during stability studies.

April 25, 2025 Admin

Problems with detecting minor defects in capsule shells during stability studies. Problems with detecting minor defects in capsule shells during stability studies. Introduction: In the pharmaceutical industry, ensuring the integrity of solid oral dosage forms, such as capsules, is crucial for maintaining drug efficacy and safety. Capsules, whether hard or soft gelatin, serve as a…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring consistent capsule appearance across validation batches.

April 23, 2025 Admin

Difficulty in ensuring consistent capsule appearance across validation batches. Difficulty in ensuring consistent capsule appearance across validation batches Introduction: In the pharmaceutical industry, ensuring the consistent appearance of capsules across validation batches is pivotal for maintaining product quality and consumer trust. Capsules, whether hard or soft gelatin, must meet stringent aesthetic standards to ensure they…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with maintaining consistent quality across different capsule sizes.

April 22, 2025 Admin

Problems with maintaining consistent quality across different capsule sizes. Problems with Maintaining Consistent Quality Across Different Capsule Sizes Introduction: Capsules, both hard and soft gelatin, remain a cornerstone of pharmaceutical delivery systems, offering precise dosage and ease of consumption. However, maintaining consistent quality across various capsule sizes presents a unique set of challenges. This article…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in preventing capsule clumping during bulk packaging.

April 22, 2025 Admin

Challenges in preventing capsule clumping during bulk packaging. Challenges in preventing capsule clumping during bulk packaging Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form due to their ease of administration and ability to deliver precise dosages. However, during the bulk packaging process, capsules can sometimes clump together, leading to quality…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in achieving reproducibility in capsule shell thickness measurements.

April 13, 2025 Admin

Difficulty in achieving reproducibility in capsule shell thickness measurements. Difficulty in Achieving Reproducibility in Capsule Shell Thickness Measurements Introduction: In the pharmaceutical industry, ensuring the consistency and quality of solid oral dosage forms such as capsules is imperative. Capsule shell thickness is a critical quality attribute that affects the integrity, dissolution, and overall performance of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with testing capsules containing high API load.

April 13, 2025 Admin

Problems with testing capsules containing high API load. Problems with testing capsules containing high API load. Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form due to their versatility and ease of administration. As the demand for high-dose medications increases, the challenge of creating capsules with a high Active Pharmaceutical Ingredient…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in assessing stability of capsules containing hygroscopic excipients.

March 28, 2025 Admin

Difficulty in assessing stability of capsules containing hygroscopic excipients. Difficulty in Assessing Stability of Capsules Containing Hygroscopic Excipients Introduction: In the pharmaceutical industry, the stability of drug formulations is paramount to ensuring efficacy and safety. Capsules, both hard and soft gelatin, are popular solid oral dosage forms due to their convenience and patient compliance. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent nitrogen distribution for capsule production.

March 21, 2025 Admin

Problems with ensuring consistent nitrogen distribution for capsule production. Problems with ensuring consistent nitrogen distribution for capsule production. Introduction: In the pharmaceutical industry, the production of solid oral dosage forms such as capsules is a complex process that requires meticulous attention to detail. Among the various factors that influence capsule quality, the consistent distribution of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent gelatin spread in soft capsule molding equipment.

March 14, 2025 Admin

Problems with ensuring consistent gelatin spread in soft capsule molding equipment. Problems with ensuring consistent gelatin spread in soft capsule molding equipment. Introduction: Soft gelatin capsules, or softgels, are a popular dosage form in the pharmaceutical and nutraceutical industries due to their ease of swallowing and ability to encapsulate a wide range of liquid or…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High rejection rates due to brittleness in capsule shells after stability testing.

March 10, 2025 Admin

High rejection rates due to brittleness in capsule shells after stability testing. High rejection rates due to brittleness in capsule shells after stability testing. Introduction: The pharmaceutical industry is ever-evolving, with a constant push towards enhancing the quality and efficacy of drug delivery systems. Capsules, both hard and soft gelatin, play a pivotal role in…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in detecting shell cracks during high-speed manufacturing.

March 9, 2025 Admin

Difficulty in detecting shell cracks during high-speed manufacturing. Difficulty in detecting shell cracks during high-speed manufacturing. Introduction: Capsules, both hard and soft gelatin, are among the most popular solid oral dosage forms in the pharmaceutical industry. Their wide acceptance is due to their versatility in delivering a variety of active pharmaceutical ingredients (APIs). However, the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms