Tag: capsule shelf-life

Problems with maintaining consistent capsule transparency over time.

May 1, 2025 Admin

Problems with maintaining consistent capsule transparency over time. Problems with maintaining consistent capsule transparency over time. Introduction: In the pharmaceutical industry, the appearance of a capsule is not merely an aesthetic concern but a critical quality attribute. Transparency in capsules, especially those made from gelatin, is vital for consumer trust and product acceptance. Over time,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating nitrogen purity for capsule storage conditions.

April 29, 2025 Admin

Challenges in validating nitrogen purity for capsule storage conditions. Challenges in validating nitrogen purity for capsule storage conditions. Introduction: In the pharmaceutical industry, maintaining the integrity and stability of solid oral dosage forms such as capsules is paramount. The use of nitrogen as an inert gas in storage environments plays a crucial role in preserving…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in monitoring capsule moisture content during accelerated stability studies.

April 28, 2025 Admin

Difficulty in monitoring capsule moisture content during accelerated stability studies. Difficulty in monitoring capsule moisture content during accelerated stability studies. Introduction: Monitoring the moisture content in capsules during accelerated stability studies is a critical component in the pharmaceutical industry. These studies are essential for predicting the shelf life and ensuring the quality, safety, and efficacy…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in predicting the impact of packaging material permeability on capsule stability.

April 28, 2025 Admin

Challenges in predicting the impact of packaging material permeability on capsule stability. Challenges in predicting the impact of packaging material permeability on capsule stability. Introduction: In the pharmaceutical industry, ensuring the stability of capsules—whether hard or soft gelatin—is a critical component of the drug development process. Packaging plays a pivotal role in preserving the integrity…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating nitrogen systems used for capsule storage.

April 26, 2025 Admin

Challenges in validating nitrogen systems used for capsule storage. Challenges in validating nitrogen systems used for capsule storage. Introduction: In the pharmaceutical industry, the storage of solid oral dosage forms such as capsules necessitates meticulous environmental control to maintain product stability and efficacy. Nitrogen systems are frequently employed to create an inert atmosphere, thereby preventing…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in evaluating stability of capsules with high oil content.

April 24, 2025 Admin

Difficulty in evaluating stability of capsules with high oil content. Difficulty in Evaluating Stability of Capsules with High Oil Content Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form, prized for their ease of use and ability to encapsulate both solid and liquid forms. However, when it comes to capsules with…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule integrity under stressed storage conditions.

April 24, 2025 Admin

Poor validation of capsule integrity under stressed storage conditions. Poor validation of capsule integrity under stressed storage conditions. Introduction: In the pharmaceutical industry, the integrity of capsules, whether hard or soft gelatin, is paramount to ensure their efficacy, safety, and quality. Capsules are a popular solid oral dosage form due to their ease of use…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in evaluating the stability of multi-particulate capsules.

April 23, 2025 Admin

Difficulty in evaluating the stability of multi-particulate capsules. Difficulty in evaluating the stability of multi-particulate capsules Introduction: In the pharmaceutical industry, ensuring the stability of drug products is crucial for maintaining their efficacy, safety, and quality over their shelf life. Multi-particulate capsules, which contain numerous small, discrete particles within a single dosage form, offer several…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor correlation between laboratory and field stability data for capsules.

April 20, 2025 Admin

Poor correlation between laboratory and field stability data for capsules. Poor correlation between laboratory and field stability data for capsules. Introduction: In the pharmaceutical industry, stability testing is a critical component that ensures the safety, efficacy, and quality of drug products throughout their shelf life. Capsules, both hard and soft gelatin, are popular solid oral…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High variability in sealing strength for capsule containers.

April 19, 2025 Admin

High variability in sealing strength for capsule containers. High variability in sealing strength for capsule containers. Introduction: In the pharmaceutical industry, ensuring the quality and integrity of solid oral dosage forms is paramount. Capsule containers, especially hard and soft gelatin capsules, are widely used due to their convenience and efficiency in drug delivery. However, one…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in assessing stability of capsules with non-aqueous fills.

April 18, 2025 Admin

Challenges in assessing stability of capsules with non-aqueous fills. Challenges in assessing stability of capsules with non-aqueous fills. Introduction: In the pharmaceutical industry, ensuring the stability of drug products is crucial for maintaining efficacy and safety. Capsules, both hard and soft gelatin, are popular solid oral dosage forms. However, when these capsules are filled with…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring compliance with regulatory guidelines for capsule packaging.

April 17, 2025 Admin

Problems with ensuring compliance with regulatory guidelines for capsule packaging. Problems with Ensuring Compliance with Regulatory Guidelines for Capsule Packaging Introduction: In the pharmaceutical industry, the packaging of solid oral dosage forms such as capsules plays a critical role in ensuring product safety, efficacy, and quality. Compliance with regulatory guidelines for capsule packaging is essential…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms