Tag: Capsule printing technology

Difficulty in Achieving Rapid Onset of Action in Hard Gelatin Capsules Addressing the Difficulty in Achieving Rapid Onset of Action in Hard Gelatin Capsules Context Hard gelatin capsules are widely…

High Risk of Microbial Contamination in Aqueous-Based Soft Gelatin Formulations Addressing the High Risk of Microbial Contamination in Aqueous-Based Soft Gelatin Formulations Context Aqueous-based formulations, such as those used in…

Lack of Suitable Surfactants for Hydrophobic APIs in Capsule Formulations Overcoming the Lack of Suitable Surfactants for Hydrophobic APIs in Capsule Formulations Context Hydrophobic active pharmaceutical ingredients (APIs) pose significant…

Variations in Capsule Dissolution Behavior Due to Excipients Grade Variability Addressing Variations in Capsule Dissolution Behavior Due to Excipients Grade Variability Context The quality and consistency of excipients are crucial…

Difficulty in Determining Optimal Capsule Fill Temperature for Soft Gelatin Capsules Overcoming the Difficulty in Determining Optimal Capsule Fill Temperature for Soft Gelatin Capsules Context Soft gelatin capsules are widely…

High Variability in Drug Release Profiles During Stability Studies Addressing High Variability in Drug Release Profiles During Stability Studies Context Stability studies are an essential part of pharmaceutical development, providing…

Limitations in Shell Material Customization for Specific APIs Overcoming Limitations in Shell Material Customization for Specific APIs Context The development of soft gelatin capsules requires careful selection and customization of…

Difficulty in Achieving Desired Uniformity in Bilayer Capsules Overcoming the Difficulty in Achieving Desired Uniformity in Bilayer Capsules Context Bilayer capsules are increasingly used in pharmaceutical formulations to combine drugs…

Poor API Solubility in Lipid-Based Excipients for Soft Gelatin Capsules Overcoming Poor API Solubility in Lipid-Based Excipients for Soft Gelatin Capsules Context Formulating lipid-based excipients in soft gelatin capsules can…

Limited Availability of Suitable Solvents for Poorly Soluble Drugs Overcoming the Limited Availability of Suitable Solvents for Poorly Soluble Drugs Context Many active pharmaceutical ingredients (APIs) exhibit poor solubility in…

High Cost of Pilot-Scale Formulation Development for Soft Gelatin Capsules Overcoming the High Cost of Pilot-Scale Formulation Development for Soft Gelatin Capsules Context Developing a soft gelatin capsule formulation at…

Challenges in Selecting Optimal Diluents for Hard Gelatin Capsules Addressing Challenges in Selecting Optimal Diluents for Hard Gelatin Capsules Context Diluents, also known as fillers, are critical excipients in hard…