Tag: capsule packaging solutions

Drug Stability Issues Due to Interaction with Gelatin Shell Components

May 2, 2025 Admin

Drug Stability Issues Due to Interaction with Gelatin Shell Components Addressing Drug Stability Issues Caused by Interaction with Gelatin Capsule Shell Components Context Drug stability is a critical consideration in the manufacturing of soft gelatin capsules, especially when the capsule shell material itself, gelatin, interacts with the active pharmaceutical ingredients (APIs) within the capsule. These…

Capsules (Hard & Soft Gelatin)

Limited Options for Solvents Suitable for Soft Gelatin Capsules

May 1, 2025 Admin

Limited Options for Solvents Suitable for Soft Gelatin Capsules Overcoming the Challenge of Limited Solvent Options for Soft Gelatin Capsules Context In pharmaceutical dosage form manufacturing, one of the challenges faced in the production of soft gelatin capsules is selecting the right solvent for dissolving or suspending the active pharmaceutical ingredient (API). The solvents used…

Capsules (Hard & Soft Gelatin)

Sensitivity of the Drug to Moisture Affecting Capsule Integrity

May 1, 2025 Admin

Sensitivity of the Drug to Moisture Affecting Capsule Integrity How Moisture Sensitivity of Drugs Affects Capsule Integrity and Solutions to Overcome It Context Moisture sensitivity of active pharmaceutical ingredients (APIs) can lead to significant challenges in capsule dosage form manufacturing, especially in soft gelatin capsules. Moisture absorption can compromise the structural integrity of the gelatin…

Capsules (Hard & Soft Gelatin)

Incompatibility of Active Ingredients with Gelatin Shell Materials

May 1, 2025 Admin

Incompatibility of Active Ingredients with Gelatin Shell Materials Addressing the Incompatibility Between Active Ingredients and Gelatin Shell Materials in Capsules Context In the pharmaceutical industry, the incompatibility between active pharmaceutical ingredients (APIs) and gelatin shell materials is a significant challenge in capsule formulation. This issue typically arises in the production of soft gelatin capsules, where…

Capsules (Hard & Soft Gelatin)

Difficulty in Achieving Uniform Drug Distribution within Capsule Fill Material

May 1, 2025 Admin

Difficulty in Achieving Uniform Drug Distribution within Capsule Fill Material Challenges in Ensuring Uniform Drug Distribution in Capsule Fill Material Context In pharmaceutical dosage form manufacturing, particularly during capsule filling, uniform drug distribution is a critical issue. This problem is encountered during the formulation of both hard and soft gelatin capsules, where ensuring consistent drug…

Capsules (Hard & Soft Gelatin)

Challenges in preventing capsule clumping during bulk packaging.

April 22, 2025 Admin

Challenges in preventing capsule clumping during bulk packaging. Challenges in preventing capsule clumping during bulk packaging Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form due to their ease of administration and ability to deliver precise dosages. However, during the bulk packaging process, capsules can sometimes clump together, leading to quality…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor alignment of capsule packs within carton trays.

April 21, 2025 Admin

Poor alignment of capsule packs within carton trays. Poor alignment of capsule packs within carton trays. Introduction: In the pharmaceutical industry, packaging plays a crucial role in maintaining product integrity and ensuring patient safety. Poor alignment of capsule packs within carton trays is a common issue that can lead to inefficiencies and potential product damage….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for validating capsule shell properties under high-humidity conditions.

April 2, 2025 Admin

Inadequate systems for validating capsule shell properties under high-humidity conditions. Inadequate systems for validating capsule shell properties under high-humidity conditions. Introduction: Capsule shell properties are critical to the performance and stability of solid oral dosage forms. In particular, the validation of these properties under high-humidity conditions is of paramount importance. High humidity can drastically affect…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with maintaining consistent pack quality during high-speed operations.

April 1, 2025 Admin

Problems with maintaining consistent pack quality during high-speed operations. Problems with Maintaining Consistent Pack Quality During High-Speed Operations Introduction: In the fast-paced world of pharmaceutical manufacturing, efficiency and quality often go hand in hand. High-speed operations, particularly in the packaging of solid oral dosage forms like capsules, are essential for meeting market demand and maintaining…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in monitoring capsule quality during long-term storage.

March 3, 2025 Admin

Difficulty in monitoring capsule quality during long-term storage. Difficulty in Monitoring Capsule Quality During Long-Term Storage Introduction: As the pharmaceutical industry continues to evolve, the importance of maintaining high-quality standards for solid oral dosage forms, particularly capsules, becomes increasingly crucial. Capsules, whether hard or soft gelatin, are popular due to their ease of administration, ability…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms