Tag: capsule manufacturing best practices

Challenges in detecting microscopic defects in gelatin shells.

April 26, 2025 Admin

Challenges in detecting microscopic defects in gelatin shells. Challenges in Detecting Microscopic Defects in Gelatin Shells Introduction: Gelatin capsules, both hard and soft, are a mainstay in pharmaceutical delivery systems, prized for their versatility and efficacy in encapsulating a diverse range of drugs. Ensuring the integrity of these capsules is crucial, as even microscopic defects…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent capsule dimensions across batches.

April 18, 2025 Admin

Problems with ensuring consistent capsule dimensions across batches. Problems with ensuring consistent capsule dimensions across batches. Introduction: In the pharmaceutical industry, the consistency of capsule dimensions is a crucial quality attribute that ensures the safety, efficacy, and reliability of the medication. Capsules, both hard and soft gelatin, are a preferred dosage form due to their…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High variability in capsule shell thickness measurements during production.

April 16, 2025 Admin

High variability in capsule shell thickness measurements during production. High Variability in Capsule Shell Thickness Measurements During Production Introduction: In the pharmaceutical industry, the production of capsules, whether hard or soft gelatin, is a critical process that demands precision and consistency. One of the significant challenges faced in this domain is the variability in capsule…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High rejection rates due to improper capsule sealing.

April 5, 2025 Admin

High rejection rates due to improper capsule sealing. High rejection rates due to improper capsule sealing. Introduction: In the pharmaceutical industry, capsules remain a popular choice for delivering medications due to their versatility, tamper-evidence, and patient compliance. However, high rejection rates due to improper capsule sealing can pose significant challenges, leading to increased production costs,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with maintaining uniform gelatin shell thickness.

April 2, 2025 Admin

Problems with maintaining uniform gelatin shell thickness. Problems with maintaining uniform gelatin shell thickness. Introduction: In the world of pharmaceutical manufacturing, ensuring the uniformity of gelatin shell thickness in capsules is pivotal. Uniform gelatin shells not only guarantee the integrity and reliability of the dosage form but also ensure patient safety and efficacy of the…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High rejection rates due to brittleness in capsule shells after stability testing.

March 10, 2025 Admin

High rejection rates due to brittleness in capsule shells after stability testing. High rejection rates due to brittleness in capsule shells after stability testing. Introduction: The pharmaceutical industry is ever-evolving, with a constant push towards enhancing the quality and efficacy of drug delivery systems. Capsules, both hard and soft gelatin, play a pivotal role in…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent gelatin spread during shell preparation validation.

March 5, 2025 Admin

Problems with ensuring consistent gelatin spread during shell preparation validation. Problems with Ensuring Consistent Gelatin Spread During Shell Preparation Validation Introduction: In the pharmaceutical industry, the production of capsules, both hard and soft gelatin, is a critical process that requires precision and consistency. One of the pivotal steps in this manufacturing process is ensuring a…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring proper alignment of capsule trays during packing.

March 2, 2025 Admin

Difficulty in ensuring proper alignment of capsule trays during packing. Difficulty in Ensuring Proper Alignment of Capsule Trays During Packing Introduction: Ensuring the proper alignment of capsule trays during the packing process is a critical component of pharmaceutical manufacturing. Proper alignment is essential to maintain the integrity of the capsules, ensure efficient packing, and comply…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms