Tag: capsule integrity

Poor reproducibility in dissolution testing results for capsules stored under stressed conditions.

May 3, 2025 Admin

Poor reproducibility in dissolution testing results for capsules stored under stressed conditions. Poor reproducibility in dissolution testing results for capsules stored under stressed conditions. Introduction: Dissolution testing is a critical quality control procedure in the pharmaceutical industry, especially for solid oral dosage forms such as capsules. It ensures that the drug releases at the intended…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for verifying capsule printing ink adhesion.

May 2, 2025 Admin

Inadequate systems for verifying capsule printing ink adhesion. Inadequate systems for verifying capsule printing ink adhesion. Introduction: In the pharmaceutical industry, capsules are a popular solid oral dosage form, offering a convenient and effective delivery system for active ingredients. However, the integrity and identification of these capsules depend heavily on the quality and adherence of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in preventing capsule discoloration during long-term storage.

May 2, 2025 Admin

Challenges in preventing capsule discoloration during long-term storage. Challenges in Preventing Capsule Discoloration During Long-Term Storage Introduction: In the pharmaceutical industry, maintaining the integrity and appearance of solid oral dosage forms, such as capsules, throughout their shelf life is crucial for ensuring product efficacy and patient compliance. Capsules, whether hard or soft gelatin, are susceptible…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate inspection systems for detecting visual defects in capsules.

May 1, 2025 Admin

Inadequate inspection systems for detecting visual defects in capsules. Inadequate Inspection Systems for Detecting Visual Defects in Capsules Introduction: In the pharmaceutical industry, ensuring the quality and safety of solid oral dosage forms, such as capsules, is paramount. Capsules, whether hard or soft gelatin, are popular for their convenience and effectiveness in delivering medications. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in predicting the impact of high humidity on capsule disintegration times.

April 30, 2025 Admin

Challenges in predicting the impact of high humidity on capsule disintegration times. Challenges in predicting the impact of high humidity on capsule disintegration times. Introduction: In the realm of pharmaceutical manufacturing, ensuring the efficacy and stability of solid oral dosage forms such as capsules is paramount. Capsules, both hard and soft gelatin, are a prevalent…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in validating nitrogen purity for capsule storage conditions.

April 29, 2025 Admin

Challenges in validating nitrogen purity for capsule storage conditions. Challenges in validating nitrogen purity for capsule storage conditions. Introduction: In the pharmaceutical industry, maintaining the integrity and stability of solid oral dosage forms such as capsules is paramount. The use of nitrogen as an inert gas in storage environments plays a crucial role in preserving…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in monitoring capsule moisture content during accelerated stability studies.

April 28, 2025 Admin

Difficulty in monitoring capsule moisture content during accelerated stability studies. Difficulty in monitoring capsule moisture content during accelerated stability studies. Introduction: Monitoring the moisture content in capsules during accelerated stability studies is a critical component in the pharmaceutical industry. These studies are essential for predicting the shelf life and ensuring the quality, safety, and efficacy…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for verifying capsule tamper-resistance features.

April 27, 2025 Admin

Inadequate systems for verifying capsule tamper-resistance features. Inadequate Systems for Verifying Capsule Tamper-Resistance Features Introduction: Ensuring the integrity and safety of pharmaceuticals is paramount in the healthcare industry. Capsules, as one of the most prevalent solid oral dosage forms, require robust tamper-resistance features to protect against contamination, counterfeiting, and unauthorized access. However, inadequate systems for…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Inadequate systems for monitoring capsule storage equipment performance.

April 25, 2025 Admin

Inadequate systems for monitoring capsule storage equipment performance. Inadequate systems for monitoring capsule storage equipment performance. Introduction: In the pharmaceutical industry, maintaining the integrity and efficacy of solid oral dosage forms, such as capsules, is paramount. Proper storage is essential to ensure that these products remain safe and effective until they reach the end-user. However,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Challenges in monitoring capsule sealing temperature for soft gelatin capsules.

April 24, 2025 Admin

Challenges in monitoring capsule sealing temperature for soft gelatin capsules. Challenges in monitoring capsule sealing temperature for soft gelatin capsules. Introduction: Soft gelatin capsules, often referred to as softgels, are a popular dosage form in the pharmaceutical industry due to their ability to encapsulate a wide range of liquid and semi-liquid formulations. The integrity and…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule integrity under stressed storage conditions.

April 24, 2025 Admin

Poor validation of capsule integrity under stressed storage conditions. Poor validation of capsule integrity under stressed storage conditions. Introduction: In the pharmaceutical industry, the integrity of capsules, whether hard or soft gelatin, is paramount to ensure their efficacy, safety, and quality. Capsules are a popular solid oral dosage form due to their ease of use…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule integrity for long-term storage conditions.

April 23, 2025 Admin

Difficulty in validating capsule integrity for long-term storage conditions. Difficulty in validating capsule integrity for long-term storage conditions. Introduction: In the pharmaceutical industry, ensuring the integrity of capsules over their shelf life is paramount. Capsules, whether hard or soft gelatin, are a preferred dosage form due to their ease of administration and ability to encapsulate…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms