Tag: capsule formulation issues

Poor correlation between laboratory and field stability data for capsules.

April 20, 2025 Admin

Poor correlation between laboratory and field stability data for capsules. Poor correlation between laboratory and field stability data for capsules. Introduction: In the pharmaceutical industry, stability testing is a critical component that ensures the safety, efficacy, and quality of drug products throughout their shelf life. Capsules, both hard and soft gelatin, are popular solid oral…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High variability in capsule shell thickness measurements during production.

April 16, 2025 Admin

High variability in capsule shell thickness measurements during production. High Variability in Capsule Shell Thickness Measurements During Production Introduction: In the pharmaceutical industry, the production of capsules, whether hard or soft gelatin, is a critical process that demands precision and consistency. One of the significant challenges faced in this domain is the variability in capsule…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in capsule weight variation validation data for soft gelatin capsules.

April 15, 2025 Admin

Poor reproducibility in capsule weight variation validation data for soft gelatin capsules. Poor reproducibility in capsule weight variation validation data for soft gelatin capsules. Introduction: The pharmaceutical industry is dedicated to maintaining the highest quality standards for drug delivery systems. Among these, soft gelatin capsules are a popular dosage form due to their easy ingestion…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with maintaining consistent dissolution profiles over the product’s shelf life.

April 13, 2025 Admin

Problems with maintaining consistent dissolution profiles over the product’s shelf life. Problems with maintaining consistent dissolution profiles over the product’s shelf life. Introduction: The dissolution profile of a pharmaceutical product is a critical parameter that impacts its efficacy and safety. Consistency in dissolution profiles over the product’s shelf life ensures that the drug is released…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in monitoring capsule weight variation.

April 8, 2025 Admin

Poor reproducibility in monitoring capsule weight variation. Poor reproducibility in monitoring capsule weight variation. Introduction: Capsules, as solid oral dosage forms, play a critical role in the pharmaceutical industry due to their ease of administration, stability, and ability to encapsulate a variety of substances. However, ensuring consistent weight and content uniformity remains a significant challenge,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in ensuring uniform capsule arrangement in multi-dose packs.

April 7, 2025 Admin

Difficulty in ensuring uniform capsule arrangement in multi-dose packs. Difficulty in ensuring uniform capsule arrangement in multi-dose packs. Introduction: In the pharmaceutical industry, the uniform arrangement of capsules in multi-dose packs is critical for ensuring dosage accuracy, patient safety, and compliance with regulatory standards. With the increasing complexity of drug formulations and the demand for…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in gelatin cross-linking data under various storage conditions.

April 4, 2025 Admin

Poor reproducibility in gelatin cross-linking data under various storage conditions. Poor Reproducibility in Gelatin Cross-Linking Data Under Various Storage Conditions Introduction: In the pharmaceutical industry, the stability and integrity of solid oral dosage forms, particularly capsules, are paramount. Gelatin, a common excipient used in hard and soft capsules, undergoes a process known as cross-linking, which…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in weight variation data for capsules over storage periods.

March 22, 2025 Admin

Poor reproducibility in weight variation data for capsules over storage periods. Poor reproducibility in weight variation data for capsules over storage periods. Introduction: In the pharmaceutical industry, ensuring the consistency and quality of solid oral dosage forms such as capsules is critical. Capsules, whether hard or soft gelatin, are widely used due to their ease…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in monitoring capsule disintegration times.

March 16, 2025 Admin

Poor reproducibility in monitoring capsule disintegration times. Poor reproducibility in monitoring capsule disintegration times. Introduction: In the realm of pharmaceutical research and manufacturing, ensuring the quality and efficacy of solid oral dosage forms is paramount. Among these, capsules, both hard and soft gelatin, are widely used due to their convenience and efficacy in drug delivery….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with ensuring consistent gelatin spread in soft capsule molding equipment.

March 14, 2025 Admin

Problems with ensuring consistent gelatin spread in soft capsule molding equipment. Problems with ensuring consistent gelatin spread in soft capsule molding equipment. Introduction: Soft gelatin capsules, or softgels, are a popular dosage form in the pharmaceutical and nutraceutical industries due to their ease of swallowing and ability to encapsulate a wide range of liquid or…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with validating capsule weight variation for soft gelatin capsules.

March 12, 2025 Admin

Problems with validating capsule weight variation for soft gelatin capsules. Problems with validating capsule weight variation for soft gelatin capsules. Introduction: In the pharmaceutical industry, ensuring the quality and consistency of solid oral dosage forms like soft gelatin capsules is crucial. These capsules are widely used due to their bioavailability and patient compliance. However, one…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule weight variation for oil-based fills.

March 10, 2025 Admin

Poor validation of capsule weight variation for oil-based fills. Poor validation of capsule weight variation for oil-based fills Introduction: In the pharmaceutical industry, the production of capsules, especially those containing oil-based fills, presents unique challenges. Capsules are a preferred solid oral dosage form due to their versatility and ability to deliver precise doses of medication….

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms