Tag: Capsule formulation challenges

Challenges in assessing the stability of capsules containing biological APIs.

April 27, 2025 Admin

Challenges in assessing the stability of capsules containing biological APIs. Challenges in assessing the stability of capsules containing biological APIs. Introduction: The pharmaceutical industry is increasingly focusing on the development of capsules containing biological Active Pharmaceutical Ingredients (APIs) due to their potential in treating various complex diseases. However, ensuring the stability of these capsules poses…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with detecting minor defects in capsule shells during stability studies.

April 25, 2025 Admin

Problems with detecting minor defects in capsule shells during stability studies. Problems with detecting minor defects in capsule shells during stability studies. Introduction: In the pharmaceutical industry, ensuring the integrity of solid oral dosage forms, such as capsules, is crucial for maintaining drug efficacy and safety. Capsules, whether hard or soft gelatin, serve as a…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor validation of capsule integrity under stressed storage conditions.

April 24, 2025 Admin

Poor validation of capsule integrity under stressed storage conditions. Poor validation of capsule integrity under stressed storage conditions. Introduction: In the pharmaceutical industry, the integrity of capsules, whether hard or soft gelatin, is paramount to ensure their efficacy, safety, and quality. Capsules are a popular solid oral dosage form due to their ease of use…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in evaluating the stability of multi-particulate capsules.

April 23, 2025 Admin

Difficulty in evaluating the stability of multi-particulate capsules. Difficulty in evaluating the stability of multi-particulate capsules Introduction: In the pharmaceutical industry, ensuring the stability of drug products is crucial for maintaining their efficacy, safety, and quality over their shelf life. Multi-particulate capsules, which contain numerous small, discrete particles within a single dosage form, offer several…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in calibrating capsule weight variation detection systems.

April 19, 2025 Admin

Difficulty in calibrating capsule weight variation detection systems. Difficulty in Calibrating Capsule Weight Variation Detection Systems Introduction: In the pharmaceutical industry, ensuring the consistent quality and weight of capsules is critical to efficacy and safety. Capsule weight variation is a significant concern, as it can impact dosage accuracy and patient outcomes. The calibration of capsule…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in monitoring fill weight for semi-solid capsule formulations.

April 16, 2025 Admin

Difficulty in monitoring fill weight for semi-solid capsule formulations. Difficulty in Monitoring Fill Weight for Semi-Solid Capsule Formulations Introduction: The pharmaceutical industry is continuously evolving with advancements in drug delivery systems. Among these, semi-solid capsule formulations have gained significant attention due to their unique advantages over traditional solid and liquid dosage forms. However, one of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Problems with detecting minor variations in capsule shell thickness over storage periods.

April 12, 2025 Admin

Problems with detecting minor variations in capsule shell thickness over storage periods. Problems with detecting minor variations in capsule shell thickness over storage periods. Introduction: In the pharmaceutical industry, capsules are a popular dosage form, offering a convenient way to deliver precise amounts of medication. However, ensuring the quality and integrity of these capsules over…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in validating capsule drying processes for multi-component formulations.

April 8, 2025 Admin

Difficulty in validating capsule drying processes for multi-component formulations. Difficulty in validating capsule drying processes for multi-component formulations. Introduction: In the pharmaceutical industry, the production of solid oral dosage forms such as capsules is a complex process that requires precise control and validation. Capsules, whether hard or soft gelatin, are a popular choice due to…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Poor reproducibility in weight variation data for capsules over storage periods.

March 22, 2025 Admin

Poor reproducibility in weight variation data for capsules over storage periods. Poor reproducibility in weight variation data for capsules over storage periods. Introduction: In the pharmaceutical industry, ensuring the consistency and quality of solid oral dosage forms such as capsules is critical. Capsules, whether hard or soft gelatin, are widely used due to their ease…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in testing for uniformity of multi-particulate capsule formulations.

March 16, 2025 Admin

Difficulty in testing for uniformity of multi-particulate capsule formulations. Difficulty in testing for uniformity of multi-particulate capsule formulations. Introduction: In the pharmaceutical industry, ensuring the uniformity of dosage units is crucial for both efficacy and safety. Multi-particulate capsule formulations are increasingly popular due to their flexibility in delivering a consistent dose of active pharmaceutical ingredients…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in testing gelatin-free capsules for uniformity.

March 7, 2025 Admin

Difficulty in testing gelatin-free capsules for uniformity. Difficulty in Testing Gelatin-Free Capsules for Uniformity Introduction: In the evolving landscape of pharmaceutical formulations, gelatin-free capsules have emerged as a significant advancement, especially for those seeking vegetarian or vegan alternatives. These capsules not only cater to dietary preferences but also overcome some of the limitations associated with…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Difficulty in testing the stability of liquid-filled capsules.

March 6, 2025 Admin

Difficulty in testing the stability of liquid-filled capsules. Difficulty in testing the stability of liquid-filled capsules. Introduction: In the pharmaceutical industry, the stability of liquid-filled capsules plays a crucial role in ensuring the efficacy, safety, and quality of medications. These capsules, whether hard or soft gelatin, serve as a popular dosage form for delivering both…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms