Tag: Analytical Testing

Troubleshooting Residual Solvent Levels in Coated Tablets

March 25, 2025 Admin

Troubleshooting Residual Solvent Levels in Coated Tablets Troubleshooting Residual Solvent Levels in Coated Tablets Introduction: Residual solvents in coated tablets are a significant concern in pharmaceutical manufacturing due to their potential impact on product safety, efficacy, and compliance with regulatory standards. These solvents, often used in the tablet coating process, must be carefully controlled to…

Solid Dosage form, Tablets

Managing Root Cause Analysis for Failures in Stability Studies

March 22, 2025 Admin

Managing Root Cause Analysis for Failures in Stability Studies Managing Root Cause Analysis for Failures in Stability Studies Introduction: In the pharmaceutical industry, stability studies are crucial to ensuring that a drug product maintains its intended quality, safety, and efficacy throughout its shelf life. Failures in stability studies can lead to significant setbacks in drug…

Solid Dosage form, Tablets

Ensuring Robustness in Content Uniformity Tests for Multi-Layer Tablets

March 20, 2025 Admin

Ensuring Robustness in Content Uniformity Tests for Multi-Layer Tablets Ensuring Robustness in Content Uniformity Tests for Multi-Layer Tablets Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of solid dosage forms such as multi-layer tablets is of paramount importance. Multi-layer tablets offer the advantage of combining different drugs or release profiles in a single…

Solid Dosage form, Tablets

Common Issues in Batch Sampling for Quality Testing of Tablets

March 19, 2025 Admin

Common Issues in Batch Sampling for Quality Testing of Tablets Common Issues in Batch Sampling for Quality Testing of Tablets Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of tablet batches is paramount. Batch sampling is a critical process that involves selecting a representative sample from a production batch to assess the quality…

Solid Dosage form, Tablets

Managing Failures in Cleaning Validation for Fluid Bed Granulation Equipment

March 19, 2025 Admin

Managing Failures in Cleaning Validation for Fluid Bed Granulation Equipment Managing Failures in Cleaning Validation for Fluid Bed Granulation Equipment Introduction: The pharmaceutical industry is heavily regulated to ensure that products are safe, effective, and of high quality. One critical aspect of pharmaceutical manufacturing is cleaning validation, particularly for complex equipment such as fluid bed…

Solid Dosage form, Tablets

Difficulty in validating capsule filling processes for multi-dose formulations.

March 18, 2025 Admin

Difficulty in validating capsule filling processes for multi-dose formulations. Difficulty in validating capsule filling processes for multi-dose formulations. Introduction: In the pharmaceutical industry, capsule filling processes for multi-dose formulations present unique challenges that require careful validation to ensure product quality and patient safety. As capsules remain a popular dosage form due to their convenience, stability,…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

High variability in content uniformity testing for multi-drug capsules.

March 18, 2025 Admin

High variability in content uniformity testing for multi-drug capsules. High Variability in Content Uniformity Testing for Multi-Drug Capsules Introduction: Content uniformity is a critical quality attribute in the manufacturing of pharmaceuticals, ensuring that each dose in a batch contains the intended amount of active pharmaceutical ingredients (APIs). In the context of multi-drug capsules, achieving content…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Ensuring Consistency in Rinse Water Sampling for Cleaning Validation

March 17, 2025 Admin

Ensuring Consistency in Rinse Water Sampling for Cleaning Validation Ensuring Consistency in Rinse Water Sampling for Cleaning Validation Introduction: In the pharmaceutical industry, maintaining the highest standards of cleanliness is crucial for ensuring product safety and efficacy. Cleaning validation, particularly rinse water sampling, plays a significant role in verifying that manufacturing equipment is free from…

Solid Dosage form, Tablets

Ensuring Consistency in Dissolution Testing for Multi-API Tablets

March 16, 2025 Admin

Ensuring Consistency in Dissolution Testing for Multi-API Tablets Ensuring Consistency in Dissolution Testing for Multi-API Tablets Introduction: Dissolution testing is a critical quality control measure in the pharmaceutical industry, particularly for tablets containing multiple active pharmaceutical ingredients (APIs). Ensuring consistency in dissolution testing is vital as it impacts the tablet’s efficacy, safety, and regulatory compliance….

Solid Dosage form, Tablets

Managing Failures in Moisture Content Tests for Coated Tablets

March 13, 2025 Admin

Managing Failures in Moisture Content Tests for Coated Tablets Managing Failures in Moisture Content Tests for Coated Tablets Introduction: Moisture content tests are an essential part of ensuring the quality, safety, and efficacy of coated tablets in pharmaceutical manufacturing. Accurate moisture levels are crucial as they impact the physical and chemical stability of the tablet,…

Solid Dosage form, Tablets

Troubleshooting Residual Solvent Issues in Sugar-Coated Tablets

March 12, 2025 Admin

Troubleshooting Residual Solvent Issues in Sugar-Coated Tablets Troubleshooting Residual Solvent Issues in Sugar-Coated Tablets Introduction: The pharmaceutical industry is continuously advancing, with an emphasis on improving the quality and safety of its products. One of the critical areas of focus is the formulation and manufacturing of solid dosage forms, particularly sugar-coated tablets. These tablets are…

Solid Dosage form, Tablets

Addressing Residual Solvent Levels in Coated Tablets During In-Process Control

March 12, 2025 Admin

Addressing Residual Solvent Levels in Coated Tablets During In-Process Control Addressing Residual Solvent Levels in Coated Tablets During In-Process Control Introduction: The pharmaceutical industry is governed by stringent regulations to ensure the safety, efficacy, and quality of products. One critical aspect of manufacturing coated tablets is managing residual solvent levels during in-process control. Residual solvents…

Solid Dosage form, Tablets