Tag: Active Pharmaceutical Ingredient

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time

April 13, 2025 Admin

Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Troubleshooting Loss of API Potency in Sugar-Coated Tablets Over Time Introduction: Sugar-coated tablets are a popular solid dosage form in the pharmaceutical industry due to their ability to mask unpleasant tastes and improve patient compliance. However, maintaining the potency of the Active Pharmaceutical Ingredient (API)…

Solid Dosage form, Tablets

Poor reproducibility in API release profiles over the product’s shelf life.

April 4, 2025 Admin

Poor reproducibility in API release profiles over the product’s shelf life. Poor reproducibility in API release profiles over the product’s shelf life. Introduction: The reproducibility of Active Pharmaceutical Ingredient (API) release profiles is a critical component in the pharmaceutical industry, particularly for solid oral dosage forms such as capsules. Ensuring consistent drug release over a…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Identifying Root Causes of Content Non-Uniformity in Tablets

March 29, 2025 Admin

Identifying Root Causes of Content Non-Uniformity in Tablets Identifying Root Causes of Content Non-Uniformity in Tablets Introduction: Content uniformity in tablets is a critical quality attribute that ensures each tablet contains an equal amount of the active pharmaceutical ingredient (API). This consistency is vital for efficacy, safety, and regulatory compliance. The challenge of maintaining content…

Solid Dosage form, Tablets

Managing Excessive Binder Use in Wet Granulation Processes

March 15, 2025 Admin

Managing Excessive Binder Use in Wet Granulation Processes Managing Excessive Binder Use in Wet Granulation Processes Introduction: In the pharmaceutical industry, wet granulation is a crucial process used to improve the flowability and compressibility of powder blends, ultimately ensuring the production of high-quality tablets. Binders play an essential role in wet granulation, providing the necessary…

Solid Dosage form, Tablets

Preventing Non-Homogeneity in Blends for Controlled Release Tablets

March 5, 2025 Admin

Preventing Non-Homogeneity in Blends for Controlled Release Tablets Preventing Non-Homogeneity in Blends for Controlled Release Tablets Introduction: Controlled release tablets are at the forefront of modern pharmaceutical development due to their ability to deliver therapeutic agents at a regulated pace, enhancing patient compliance and therapeutic efficacy. However, achieving uniform distribution of active pharmaceutical ingredients (APIs)…

Solid Dosage form, Tablets

Addressing Challenges in API Loading During Granulation

March 2, 2025 Admin

Addressing Challenges in API Loading During Granulation Addressing Challenges in API Loading During Granulation Introduction: In the pharmaceutical industry, granulation is a critical process in the production of solid dosage forms such as tablets. Ensuring uniform distribution of the Active Pharmaceutical Ingredient (API) is vital for achieving the desired therapeutic effects and ensuring patient safety….

Solid Dosage form, Tablets

What are the main components of a capsule formulation?

July 26, 2023July 31, 2023 Admin

Main Components of a Capsule Formulation A capsule formulation typically consists of the following main components: Active Pharmaceutical Ingredient (API): The API is the primary drug or therapeutic substance that provides the intended pharmacological effect. It is the active substance responsible for treating the medical condition. Excipients: Excipients are inactive substances present in the capsule…

Capsules (Hard & Soft Gelatin)