Preventing Overwrapping Defects in Immediate Release Tablet Packs

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Preventing Overwrapping Defects in Immediate Release Tablet Packs Preventing Overwrapping Defects in Immediate Release Tablet Packs Introduction: In the pharmaceutical industry, packaging plays a pivotal role in ensuring the safety, efficacy, and quality of drug products. Immediate release tablet packs are no exception. These packs are designed to safeguard tablets from environmental factors such as…

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Solid Dosage form, Tablets

Issues with Excessive Foaming During Gelatin Preparation

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Issues with Excessive Foaming During Gelatin Preparation Addressing Issues with Excessive Foaming During Gelatin Preparation Context Excessive foaming during the preparation of gelatin for soft gelatin capsules is a common issue that can disrupt the encapsulation process. Foam formation in the gelatin solution can cause problems such as inconsistent capsule shells, clogging of equipment, and…

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Capsules (Hard & Soft Gelatin)

Ensuring Compliance with GMP Standards in Cleaning Validation Documentation

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Ensuring Compliance with GMP Standards in Cleaning Validation Documentation Ensuring Compliance with GMP Standards in Cleaning Validation Documentation Introduction: In the pharmaceutical industry, ensuring that every product is manufactured to the highest quality is paramount. This commitment to quality extends to the cleaning processes employed within manufacturing facilities. Cleaning validation is a critical component of…

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Solid Dosage form, Tablets

Addressing Coating Delamination in Sugar-Coated Tablets Under Humid Conditions

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Addressing Coating Delamination in Sugar-Coated Tablets Under Humid Conditions Addressing Coating Delamination in Sugar-Coated Tablets Under Humid Conditions Introduction: In the pharmaceutical industry, sugar-coated tablets are a popular dosage form due to their aesthetic appeal and ability to mask unpleasant tastes and odors. However, coating delamination, especially under humid conditions, poses significant challenges to manufacturers….

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Solid Dosage form, Tablets

Difficulty in Maintaining Consistent Pressure in Filling Pumps for Soft Gelatin Capsules

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Difficulty in Maintaining Consistent Pressure in Filling Pumps for Soft Gelatin Capsules Addressing Difficulty in Maintaining Consistent Pressure in Filling Pumps for Soft Gelatin Capsules Context In the manufacturing of soft gelatin capsules, maintaining consistent pressure in the filling pumps is crucial for ensuring accurate and uniform dosing of the fill material. Variations in pressure…

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Capsules (Hard & Soft Gelatin)

Addressing Residual Binder Accumulation in Blending Machines During Cleaning Validation

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Addressing Residual Binder Accumulation in Blending Machines During Cleaning Validation Addressing Residual Binder Accumulation in Blending Machines During Cleaning Validation Introduction: In the pharmaceutical industry, ensuring the cleanliness of manufacturing equipment is crucial to maintain product quality and safety. One of the persistent challenges faced during the tablet production process is the accumulation of residual…

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Solid Dosage form, Tablets

Frequent Replacement of Dies in Soft Gelatin Manufacturing

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Frequent Replacement of Dies in Soft Gelatin Manufacturing Addressing Frequent Replacement of Dies in Soft Gelatin Manufacturing Context In soft gelatin capsule manufacturing, dies are used to form the capsule shells by molding the gelatin mixture. Over time, dies can wear out or become damaged, leading to the need for frequent replacements. This issue not…

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Capsules (Hard & Soft Gelatin)

Managing Tablet Orientation in High-Speed Blister Machines

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Managing Tablet Orientation in High-Speed Blister Machines Managing Tablet Orientation in High-Speed Blister Machines Introduction: In the pharmaceutical industry, the precision and efficiency of packaging processes are crucial for ensuring product quality and regulatory compliance. High-speed blister machines play a vital role in the packaging of tablets, offering a reliable and efficient means of protecting…

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Solid Dosage form, Tablets

Ensuring Compliance with Residual Limits in Equipment Validation Studies

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Ensuring Compliance with Residual Limits in Equipment Validation Studies Ensuring Compliance with Residual Limits in Equipment Validation Studies Introduction: In the pharmaceutical industry, ensuring compliance with residual limits during equipment validation studies is crucial to maintaining product quality and safeguarding patient safety. Equipment used in the production of solid dosage forms, such as tablets, must…

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Solid Dosage form, Tablets

High Energy Consumption in Soft Gelatin Capsule Drying Processes

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High Energy Consumption in Soft Gelatin Capsule Drying Processes Addressing High Energy Consumption in Soft Gelatin Capsule Drying Processes Context The drying process in soft gelatin capsule manufacturing plays a vital role in determining the final quality of the capsules. However, this process is often energy-intensive, as it requires consistent temperature and humidity control to…

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Capsules (Hard & Soft Gelatin)

Ensuring Tamper-Proof Sealing for Tablet Blister Packs

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Ensuring Tamper-Proof Sealing for Tablet Blister Packs Ensuring Tamper-Proof Sealing for Tablet Blister Packs Introduction: In the realm of pharmaceutical packaging, ensuring the integrity and security of tablet blister packs is of paramount importance. Blister packs are a popular choice for packaging tablets due to their ability to protect the product from environmental factors, ensure…

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Solid Dosage form, Tablets

Addressing Residual API Issues in Wet Granulation Vessels After Cleaning

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Addressing Residual API Issues in Wet Granulation Vessels After Cleaning Addressing Residual API Issues in Wet Granulation Vessels After Cleaning Introduction: In the pharmaceutical industry, wet granulation is a critical process for producing solid dosage forms like tablets. This method helps in improving the compressibility and flowability of the powder mix. However, post-production cleaning of…

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Solid Dosage form, Tablets