Author: Admin

Problems with ensuring accurate calibration of capsule weight monitoring systems.

March 14, 2025 Admin

Problems with ensuring accurate calibration of capsule weight monitoring systems. Problems with ensuring accurate calibration of capsule weight monitoring systems. Introduction: In the pharmaceutical industry, maintaining the precise weight of capsules is crucial to ensure the efficacy and safety of medications. Capsule weight monitoring systems are employed to achieve this goal, but ensuring their accurate…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Failures in Moisture Content Tests for Sugar-Coated Tablets

March 14, 2025 Admin

Resolving Failures in Moisture Content Tests for Sugar-Coated Tablets Resolving Failures in Moisture Content Tests for Sugar-Coated Tablets Introduction: In the pharmaceutical industry, sugar-coated tablets are a popular dosage form due to their aesthetic appeal and ability to mask unpleasant tastes. However, maintaining the correct moisture content in these tablets is crucial, as it affects…

Solid Dosage form, Tablets

Troubleshooting Residual Binder Issues in Granulation Equipment During Validation

March 14, 2025 Admin

Troubleshooting Residual Binder Issues in Granulation Equipment During Validation Troubleshooting Residual Binder Issues in Granulation Equipment During Validation Introduction: In the pharmaceutical industry, ensuring the quality and efficacy of solid dosage forms like tablets is paramount. Granulation is a critical process in tablet manufacturing, where powders are agglomerated to form granules, enhancing flowability and compressibility…

Solid Dosage form, Tablets

Challenges in validating capsule coating processes.

March 14, 2025 Admin

Challenges in validating capsule coating processes. Challenges in Validating Capsule Coating Processes Introduction: In the pharmaceutical industry, the coating of capsules—both hard and soft gelatin—is a critical step in ensuring product stability, controlled release, and patient compliance. Validating these coating processes is essential for maintaining product efficacy and safety. This article explores the challenges of…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Selecting the Optimal Binder for Granulation Processes

March 14, 2025 Admin

Selecting the Optimal Binder for Granulation Processes Expert Guide: Selecting the Optimal Binder for Granulation Processes Overview: Granulation is a crucial step in pharmaceutical tablet manufacturing, ensuring proper powder flowability, compressibility, and uniformity. The selection of a suitable binder is critical to achieving the desired granule characteristics, as binders help in particle adhesion, mechanical strength,…

Tablets

Preventing Explosive Failures in Pressurized Aerosols

March 14, 2025 Admin

Preventing Explosive Failures in Pressurized Aerosols FAQ: How to Mitigate Risks of Explosive Failures in Aerosol Cans Why Are Explosive Failures a Risk in Pressurized Aerosols? Pressurized aerosol formulations rely on highly compressed gases or propellants. Improper handling, storage, or design flaws can cause explosions, posing significant safety hazards to manufacturers, retailers, and consumers. Preventing…

Aerosol Formulations

Poor communication between quality assurance and production teams.

March 14, 2025 Admin

Poor communication between quality assurance and production teams. Poor communication between quality assurance and production teams. Introduction: In pharmaceutical manufacturing, the synergy between quality assurance (QA) and production teams is pivotal for ensuring the safety, efficacy, and quality of products. However, poor communication between these departments can lead to significant challenges, including compliance risks, production…

Capsules (Hard & Soft Gelatin), Solid Oral Dosage Forms

Resolving Over-Lubrication Issues in Immediate Release Tablets

March 14, 2025 Admin

Resolving Over-Lubrication Issues in Immediate Release Tablets Resolving Over-Lubrication Issues in Immediate Release Tablets Introduction: Immediate release tablets are a mainstay in the pharmaceutical industry, offering quick onset of action and ease of administration. However, the formulation and manufacturing of these tablets present unique challenges, particularly with lubrication. Over-lubrication can compromise tablet quality, affecting disintegration…

Solid Dosage form, Tablets

Troubleshooting Over-Drying in Coated Tablets During Finishing

March 14, 2025 Admin

Troubleshooting Over-Drying in Coated Tablets During Finishing Troubleshooting Over-Drying in Coated Tablets During Finishing Introduction: The pharmaceutical industry is continually innovating to ensure the highest quality of products. Among the various dosage forms, coated tablets are one of the most prevalent, owing to their aesthetic appeal, ease of swallowing, and controlled release capabilities. However, the…

Solid Dosage form, Tablets

How to Use Artificial Intelligence for Tablet Process Optimization

March 14, 2025 Admin

How to Use Artificial Intelligence for Tablet Process Optimization Step-by-Step Guide to Using Artificial Intelligence in Tablet Process Optimization Why Use Artificial Intelligence in Tablet Manufacturing? Artificial intelligence (AI) in tablet manufacturing leverages data-driven techniques to enhance efficiency, improve product quality, and reduce costs. AI-driven systems analyze complex datasets from manufacturing processes to identify patterns,…

Tablets

Validating Rinse Sampling Procedures in Cleaning Validation for Film-Coated Tablets

March 14, 2025 Admin

Validating Rinse Sampling Procedures in Cleaning Validation for Film-Coated Tablets Validating Rinse Sampling Procedures in Cleaning Validation for Film-Coated Tablets Introduction: In the pharmaceutical industry, ensuring the cleanliness of manufacturing equipment is crucial, especially when producing film-coated tablets. Cleaning validation, particularly rinse sampling procedures, plays a pivotal role in confirming that any residues from previous…

Solid Dosage form, Tablets

What Are the Duties of Principal Investigators in GLP Studies?

March 14, 2025 Admin

What Are the Duties of Principal Investigators in GLP Studies? Understanding the Role of Principal Investigators in GLP Studies Introduction In Good Laboratory Practices in pharma (GLP), the Principal Investigator (PI) plays a vital role in multi-site studies by managing specific phases of the study at their respective locations. While the Study Director retains overall…

GLP Guidelines