Author: Admin

What is disintegration test in tablet formulation?

July 28, 2023 Admin

Disintegration Test in Tablet Formulation The disintegration test is a crucial quality control test conducted during tablet formulation to assess how quickly a tablet disintegrates into small particles when exposed to a specified fluid environment. The disintegration time is an essential parameter that influences drug release and absorption rates. This test ensures that the tablet…

Tablets

How is a tablet’s hardness determined?

July 28, 2023 Admin

Determination of Tablet Hardness Tablet hardness, also known as tablet crushing strength, is a critical quality attribute that determines the tablet’s ability to withstand mechanical stress during handling, packaging, and transportation. The hardness of a tablet directly influences its disintegration and dissolution properties, as well as patient compliance. Various methods are used to determine tablet…

Tablets

What are the advantages of dry granulation over wet granulation?

July 28, 2023 Admin

Advantages of Dry Granulation Over Wet Granulation Advantages Dry Granulation Wet Granulation Drug Stability Dry granulation is suitable for moisture-sensitive drugs as it avoids exposure to water or solvents, preserving drug stability. Wet granulation may cause degradation of moisture-sensitive drugs due to exposure to water or solvents. Process Efficiency Dry granulation requires fewer equipment and…

Tablets

Explain the process of dry granulation in tablet manufacturing

July 28, 2023 Admin

Dry Granulation in Tablet Manufacturing Dry granulation, also known as pre-compression or slugging, is a tablet manufacturing process that involves compacting the powder blend without using any liquid binder. This method is suitable for drugs that are sensitive to moisture or heat and cannot undergo wet granulation. Dry granulation is particularly advantageous when dealing with…

Tablets

Explain the process of wet granulation in tablet manufacturing

July 28, 2023 Admin

Wet Granulation in Tablet Manufacturing Wet granulation is a widely used process in tablet manufacturing that involves the agglomeration of powder particles to form granules. This process is essential for improving the flow properties, compressibility, and uniformity of the drug formulation, ultimately leading to the production of high-quality tablets. Here’s a step-by-step explanation of the…

Tablets

What are immediate-release tablets?

July 28, 2023 Admin

Immediate-Release Tablets Immediate-release tablets are a common type of pharmaceutical dosage form designed to release the active drug ingredient quickly after ingestion. These tablets are formulated to disintegrate rapidly in the gastrointestinal tract, allowing the drug to be absorbed into the bloodstream at a faster rate compared to other oral dosage forms. Characteristics of Immediate-Release…

Tablets

Explain the role of GMP in preventing contamination and cross-contamination.

July 27, 2023 Admin

‘GMP helps in Preventing Contamination and Cross-Contamination’ Good Manufacturing Practice (GMP) plays a crucial role in preventing contamination and cross-contamination in pharmaceutical manufacturing. Contamination refers to the unintended presence of harmful substances or impurities, while cross-contamination refers to the transfer of contaminants between different materials, equipment, or products. GMP guidelines provide a framework to ensure…

GMP Guidelines

How do GMP guidelines ensure product quality and safety?

July 27, 2023July 28, 2023 Admin

‘GMP Guidelines Ensures Product Quality and Safety ‘ Good Manufacturing Practice (GMP) guidelines play a critical role in ensuring the quality and safety of pharmaceutical products throughout their manufacturing process. These guidelines are designed to establish a standardized approach that pharmaceutical companies must follow to maintain the highest level of quality and safety in their…

GMP Guidelines

What are the key principles of GMP?

July 27, 2023 Admin

Key Principles of Good Manufacturing Practice (GMP) in Pharmaceutical Manufacturing In pharmaceutical manufacturing, adhering to Good Manufacturing Practice (GMP) is crucial to ensure the quality, safety, and efficacy of medicinal products. GMP provides a set of guidelines and standards that pharmaceutical companies must follow during the manufacturing process. Here are the key principles of GMP:…

GMP Guidelines

What are the requirements for premises and equipment under Schedule M?

July 27, 2023July 27, 2023 Admin

Premises and Equipment Requirements in Pharmaceutical Manufacturing Let’s explore the specific requirements for premises and equipment under Schedule M: 1. Premises Requirements Under Schedule M, the manufacturing premises must meet specific criteria to ensure a controlled and suitable environment for drug production. The following are the key requirements for premises: Location: The manufacturing facility should…

Schedule M

How is compliance with Schedule M ensured during drug manufacturing?

July 27, 2023 Admin

Ensuring Compliance with Schedule M during Drug Manufacturing Schedule M lays down stringent guidelines and requirements to ensure the quality, safety, and efficacy of drugs produced in India. Manufacturers must adhere to these guidelines throughout the manufacturing process to maintain compliance. Let’s explore the key measures taken to ensure compliance with Schedule M during drug…

Schedule M

What types of drugs and pharmaceuticals does Schedule M apply to?

July 27, 2023 Admin

Types of Drugs and Pharmaceuticals Covered by Schedule M Schedule M, a crucial aspect of the regulatory framework under the Drugs and Cosmetics Act, 1940, applies to various types of drugs and pharmaceuticals. The following are the main categories of drugs and pharmaceuticals that fall under the purview of Schedule M: 1. Allopathic Medicines Schedule…

Schedule M